Synopsis of recent research by authors named "Zijie Jin"
- Zijie Jin's research primarily focuses on the roles of sodium-glucose cotransporter 2 (SGLT2) inhibitors in managing liver and kidney complications associated with diabetes, particularly their mechanisms in ameliorating nonalcoholic fatty liver disease (NAFLD) and diabetic renal injury.
- Recent studies highlight dapagliflozin's protective effects against hepatic steatosis and kidney damage by suppressing lipid and bile acid synthesis and reducing inflammation, thereby addressing significant gaps in pharmacotherapy for these conditions.
- Jin also contributes to computational biology, evidenced by the development of TAGET, a toolkit for analyzing full-length transcripts from long-read sequencing, enhancing the analysis and understanding of transcriptomic data in various disease contexts.