Publications by authors named "Zijiang Guo"
Article Synopsis
- - The study investigates how CDC42 levels in blood relate to sepsis, inflammation, and multi-organ dysfunction by analyzing samples from 145 sepsis patients and 50 healthy controls.
- - Results show that CDC42 levels are significantly lower in sepsis patients and can predict sepsis risk and mortality, with a strong statistical correlation to various inflammatory markers and organ function scores.
- - The findings suggest that CDC42 could serve as a useful prognostic biomarker for assessing the severity and potential outcomes of sepsis, indicating higher mortality risk and multi-organ dysfunction.
Aim: Human CXCR3, a seven-transmembrane segment (7TMS), is predominantly expressed in Th1-mediated responses. Interferon-gamma-inducible protein 10 (IP-10) is an important ligand for CXCR3. Their interaction is pivotal for leukocyte migration and activation.
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