Publications by authors named "Zijia Feng"
Front Pharmacol
September 2023
Article Synopsis
- * Key methods include checkpoint inhibitor antibodies and chimeric antigen receptor T cell therapies, but there are challenges like limited effectiveness and high toxicity, especially for solid tumors like osteosarcoma.
- * Nanoparticle drug delivery systems provide a promising new strategy by targeting immune cells that suppress anti-tumor responses, enhancing the effectiveness of immunotherapy through various mechanisms including promoting cell death and activating immune signals.
Front Immunol
August 2023
Article Synopsis
- Macrophages are versatile immune cells that adapt their functions based on their environment, playing a crucial role in managing disease progression and tissue balance.
- Different macrophage subtypes have specific roles, and dysfunction or imbalance among these types, especially between M1 and M2, can lead to diseases, particularly in skeletal muscle.
- The review emphasizes the importance of understanding macrophage interactions and suggests strategies to target them for reducing damage and fibrosis in muscular disorders, aiming to improve tissue health.
