Publications by authors named "Ziheng Yuan"
The striking rise of infections caused by multidrug-resistant pathogens has evolved as a serious threat to public health worldwide. To develop new antibacterials to combat multidrug-resistant bacteria, a novel class of amphiphilic chalcone derivatives serving as antimicrobial peptidomimetics was designed and synthesized. Among them, the most promising compound 14b displayed broad-spectrum antimicrobial activity against both Gram-positive bacteria (MICs = 0.
View Article and Find Full Text PDFArticle Synopsis
- Smoking negatively impacts lung function in patients with idiopathic pulmonary fibrosis (IPF), as shown by a study using genetic data and smoking habits.
- The study analyzed large datasets and found that a higher lifetime smoking index is linked to lower diffusing capacity of the lungs for carbon monoxide (DLCO) in these patients.
- Researchers encourage IPF patients to quit smoking to potentially slow down the disease's progression and improve their lung health.
Background: Aldehyde oxidase 1 (AOX1) is associated with various pathophysiological processes, including cancer. Specifically, AOX1 has been demonstrated to have a close relationship with the progression of certain cancers. However, the expression, function, and mechanisms of action of AOX1 in gallbladder cancer (GBC) remain unclear.
View Article and Find Full Text PDF