Anion-mediated approach to overcome oxidation in ether electrolytes for high-voltage sodium-ion batteries.

The ether-based electrolytes are acknowledged for their compatibility with a diverse array of sodium-ion battery anodes, as well as their capability to enable efficient and reversible electrochemical reactions. However, they encounter a challenge of oxidation at high voltages. We find that a standard diglyme-based electrolyte starts to oxidize and break down at voltages exceeding 3.

Integrated skin metabolomics and network pharmacology to explore the mechanisms of Goupi Plaster for treating knee osteoarthritis.

Background And Aim: Goupi Plaster (GP) is topical traditional Chinese medicine preparation. It has been used to treat Knee Osteoarthritis (KOA) in clinical practice of traditional Chinese medicine (TCM). However, the mechanisms of GP relieve KOA are poorly understood.

Corrigendum to "Integrated skin metabolomics and network pharmacology to explore the mechanisms of Goupi Plaster for treating knee osteoarthritis" [J Tradit, Complementary Altern Med 14 (6) (2024) 675-686].

[This corrects the article DOI: 10.1016/j.jtcme.

Low-Quality Sensor Data-Based Semi-Supervised Learning for Medical Image Segmentation.

Traditional medical image sensors face multiple challenges. First, these sensors typically rely on large amounts of labeled data, which are time-consuming and costly to obtain. Second, when the data volume and image size are large, traditional sensors have limited computational power, making it difficult to effectively train and infer models.

, and in fleas from the long-tailed ground squirrel () in northwestern China.

Fleas are known to be vectors for a variety of pathogens in veterinary medicine. However, no information is available on the presence of and Trypanosomatidae in fleas of the long-tailed ground squirrel (LTGR, ). The present study shows detection of these pathogens in LTGR fleas.

Qualitative and quantitative analysis of chemical constituents in goupi plaster prepared by various extraction methods using UPLC-Q-Exactive-MS and UPLC-MS/MS.

Goupi plaster, a representative preparation of black plaster, has demonstrated promising effects in treating knee osteoarthritis. However, high temperature used in traditional frying extraction may cause decomposition of its effective components, thus limiting the efficacy. This study aimed to explore the scientific nature of the traditional preparation technology of Goupi plaster, and to compare the effects of different extraction methods on the types of chemical components and the content of index components.

Sustainable Polymers with High Performance and Infinite Scalability.

Our society has been pursuing high-performance biodegradable polymers made from facile methods and readily available monomers. Here, we demonstrate a library of enzyme-degradable polymers with desirable properties from the first reported step polyaddition of diamines, COS, and diacrylates. The polymers contain in-chain ester and thiourethane groups, which can serve as lipase-degradation and hydrogen-bonding physical crosslinking points, respectively, resulting in possible biodegradability as well as upgraded mechanical and thermal properties.

Research on integrated inventory transportation optimization of inbound logistics via a VMI-TPL model of an existing enterprise.

Third-party logistics companies face a challenging task in minimizing inventory transportation costs due to the complexities of managing numerous suppliers. Effectively optimizing costs becomes a formidable problem for such companies. This empirical research has yielded strategies for minimizing the inventory transportation cost specifically for company D.

The Intermediate Connection of Subcells in Si-based Tandem Solar Cells.

Tandem solar cells are rationally designed and fabricated by stacking multiple subcells to achieve power conversion efficiency well above the Shockley-Queisser (SQ) limit. There is a large selection pool for the subcell candidates, such as Si, III-V, Kesterite, Perovskite, and organic solar cells. A series of different combinations of these subcells have been successfully demonstrated in practical tandem solar cell devices.

Modular Alcohol Click Chemistry Enables Facile Synthesis of Recyclable Polymers with Tunable Structure.

The facile synthesis of chemically recyclable polymers derived from sustainable feedstocks presents enormous challenges. Here, we develop a novel, modular, and efficient click reaction for connecting primary, secondary, or tertiary alcohols with activated alkenes via a bridge molecule of carbonyl sulfide (COS). The click reaction is successfully applied to synthesize a series of recyclable polymers by the step polyaddition of diols, diacrylates, and COS.

Lessons from discovery of true ADAR RNA editing sites in a human cell line.

Background: Conversion or editing of adenosine (A) into inosine (I) catalyzed by specialized cellular enzymes represents one of the most common post-transcriptional RNA modifications with emerging connection to disease. A-to-I conversions can happen at specific sites and lead to increase in proteome diversity and changes in RNA stability, splicing, and regulation. Such sites can be detected as adenine-to-guanine sequence changes by next-generation RNA sequencing which resulted in millions reported sites from multiple genome-wide surveys.

Bifacial and Semitransparent Sb (S,Se) Solar Cells for Single-Junction and Tandem Photovoltaic Applications.

Thin-film solar cells are expected to play a significant role in the space industry, building integrated photovoltaic (BIPV), indoor applications, and tandem solar cells, where bifaciality and semitransparency are highly desired. Sb (S,Se) has emerged as a promising new photovoltaic (PV) material for its high absorption coefficient, tunable bandgap, and nontoxic and earth-abundant constituents. However, high-efficiency Sb (S,Se) solar cells exclusively employ monofacial architectures, leaving a considerable gap toward large-scale application in aforementioned fields.

Simultaneous Pyrolysis of Coal and Biomass in a Drop-Tube-Fixed-Bed Reactor.

Copyrolysis of coal and biomass has been extensively studied to exploit its inherent synergistic effects; however, the different pyrolysis temperature zones of coal and biomass seriously affect the realization of these effects. Therefore, a new copyrolysis method (preheating the coal to a certain temperature and then adding the biomass in a drop-tube-fixed-bed reactor, denoted as M1) was designed herein to achieve "simultaneous" pyrolysis of coal and biomass. The yields of products and the characteristics of M1-produced tar were estimated and compared with those of tar obtained by fixed-bed-reactor (denoted as M2)-based copyrolysis.

Interactions between Coal and Solvent during the Solvent Extraction of Coal in View of Free Radicals.

In this study, variations in the free radical concentration, degree of swelling (), and extraction yield of Buertai coal (C%, 80.4%) in 11 solvents with different characteristics were determined to investigate the interaction between the coal and solvent, as well as the bond cleavage during solvent extraction. Derivative thermogravimetry (DTG) results for the residues and raw coal were compared to confirm whether the covalent bond breaks during solvent extraction.

Par complex cluster formation mediated by phase separation.

The evolutionarily conserved Par3/Par6/aPKC complex regulates the polarity establishment of diverse cell types and distinct polarity-driven functions. However, how the Par complex is concentrated beneath the membrane to initiate cell polarization remains unclear. Here we show that the Par complex exhibits cell cycle-dependent condensation in Drosophila neuroblasts, driven by liquid-liquid phase separation.

Recovery of Yam Soluble Protein from Yam Starch Processing Wastewater.

Over the past two decades, many studies have shown that the yam storage protein dioscorin, which is abundant in the wastewater of starch processing, exhibits many biological activities both in vitro and in vivo. In the present study, the acid-precipitation method was optimized using Box-Behnken design (BBD) combined with response surface methodology (RSM) for the recovery of yam soluble protein (YSP) from wastewater. The experimental yield of YSP reached 57.

Foliar application is an effective method for incorporating selenium into peanut leaf proteins with antioxidant activities.

Proteins were extracted from Se-enriched peanut leaves, an agro-byproduct, and the foliar application of sodium selenite was indicated to be an effective method to incorporate Se into leaf selenoproteins with 75-80% incorporation rates. After trypsin digestion, the most abundant proteins from Se-enriched peanut leaf (PSPL) were identified as pathogenesis-related class 10 proteins, Ara h 8 allergen and its isoforms, using LC-MS/MS. The Se species in both the low Se PSPL and high Se PSPL were determined to be selenomethionine (SeMet), methylselenocysteine (MeSeCys) and selenocystine (SeCys) with SeMet (15.

A multi-lock inhibitory mechanism for fine-tuning enzyme activities of the HECT family E3 ligases.

HECT E3 ligases control the degradation and functioning of numerous oncogenic/tumor-suppressive factors and signaling proteins, and their activities must be tightly regulated to prevent cancers and other diseases. Here we show that the Nedd4 family HECT E3 WWP1 adopts an autoinhibited state, in which its multiple WW domains sequester HECT using a multi-lock mechanism. Removing WW2 or WW34 led to a partial activation of WWP1.

Basal condensation of Numb and Pon complex via phase transition during Drosophila neuroblast asymmetric division.

Uneven distribution and local concentration of protein complexes on distinct membrane cortices is a fundamental property in numerous biological processes, including Drosophila neuroblast (NB) asymmetric cell divisions and cell polarity in general. In NBs, the cell fate determinant Numb forms a basal crescent together with Pon and is segregated into the basal daughter cell to initiate its differentiation. Here we discover that Numb PTB domain, using two distinct binding surfaces, recognizes repeating motifs within Pon in a previously unrecognized mode.

Structural determinants controlling 14-3-3 recruitment to the endocytic adaptor Numb and dissociation of the Numb·α-adaptin complex.

Traffic of cargo across membranes helps establish, maintain, and reorganize distinct cellular compartments and is fundamental to many metabolic processes. The cargo-selective endocytic adaptor Numb participates in clathrin-dependent endocytosis by attaching cargoes to the clathrin adaptor α-adaptin. The phosphorylation of Numb at Ser and Ser recruits the regulatory protein 14-3-3, accompanied by the dissociation of Numb from α-adaptin and Numb's translocation from the cortical membrane to the cytosol.

[Sulfated modification and anticoagulant activity in vitro of sulfated glucan isolated from the aqueous extract of Hedysarum polybotrys].

SHG was sulfated by chlorosulfonic acid-pyridine method, and six samples which we got were prepared in different reaction conditions. There is a characteristic absorption peak near 260 nm in UV spectra and there are two characteristic absorption peaks near 1240 cm(-1) and 810 cm(-1) in the FT-IR. Degree of sulfation (DS) was calculated by elemental analysis and turbidimetry.