Publications by authors named "Zihang Sheng"
Full-Spectrum Surveillance of Pre-Treatment HIV Drug Resistance in Southeastern China.
Pharmaceuticals (Basel)
July 2024
Article Synopsis
- - The study examines pre-treatment drug resistance (PDR) in newly diagnosed HIV-1 individuals in Wenzhou, China, finding a total PDR prevalence of 6.5% for any antiretroviral drug.
- - Among specific drug classes, the highest resistance was noted for non-nucleoside reverse transcriptase inhibitors (NNRTIs) at 4.1%, while resistance rates for nucleoside reverse transcriptase inhibitors (NRTIs), protease inhibitors (PIs), and integrase strand transfer inhibitors (INSTIs) were significantly lower.
- - The findings suggest a need for more non-NNRTI-based ART treatments and emphasize the importance of genotypic resistance testing prior to starting