Line integral compressed ultrafast photography for large time-scale measurements.

Compressed ultrafast photography (CUP) has attracted significant attention in the field of ultrafast optical imaging but is inherently constrained by a trade-off between sequence depth and spatial resolution. To address this limitation, we present a novel, to the best of our knowledge, system called spatial line integral CUP (LI-CUP). LI-CUP utilizes a cylindrical lens to compress each encoded time-slice frame into a spatial line, which is then recorded by a streak camera with a narrow slit.

Mechanism insight into sulfidated nano zero-valent iron/biochar activated persulfate for highly efficient degradation of p-chloroaniline.

Nano zero-valent iron (nZVI) and its composites utilized as persulfate (PS) activators has attracted extensive attention for the complete oxidative degradation of organic contaminants. However, the intrinsic agglomeration and the passivation layer on nZVI surface seriously impeded the electronic transmission performance, which significantly decreased the utilization efficiency of nZVI. Herein, sulfidated nano zero-valent iron/biochar (S-nZVI/BC) was prepared by the co-sulfuration method via liquid phase reduction approach to promote PS activation for p-chloroaniline (PCA) degradation.

Digital Health Interventions to Improve Mental Health in Patients With Cancer: Umbrella Review.

Background: Mental health plays a key role across the cancer care continuum, from prognosis and active treatment to survivorship and palliative care. Digital health technologies offer an appealing, cost-effective tool to address psychological needs.

Objective: This umbrella review aims to summarize and evaluate the available evidence on the efficacy of digital health interventions for improving mental health and psychosocial outcomes for populations with cancer.

A novel method for the rapid determination of phenolic compounds based on the nanozyme with laccase-like activity.

Phenolic compounds are prevalent in domestic and industrial effluents, leading a serious environmental hazard. Paper-based analysis device mediated by nanozymes has shown great potential in portable visual determination of phenolic compounds in the environment. In this work, we used nicotinic acid derivatives such as pyridine-2,3-dicarboxylic acid, 2-methylnicotinic acid and 2-aminonicotinic acid by coordinating copper (II) acetate monohydrate coordination to obtain Cu2-COOHNA, Cu2-CHNA, Cu2-ANA nanozymes with laccase-activity.

Real world pharmacovigilance assessment of drug related macular degeneration risks.

Macular degeneration is a leading cause of irreversible vision loss, significantly impacting quality of life. To enhance clinical practice and reduce the risk of drug-related macular degeneration, we analyzed drug-related trends using real-world data. Disproportionality analysis of adverse event reports from the FDA Adverse Event Reporting System (FAERS, 2004-2023) identified 67,683 cases involving 1402 drugs.

Detection of differences in physical symptoms between depressed and undepressed patients with breast cancer: a study using K-medoids clustering.

Background: To detect the differences in physical symptoms between depressed and undepressed patients with breast cancer (BC), including common symptoms, co-occurring symptoms, and symptom clusters based on texts derived from social media and expressive writing.

Methods: A total of 1830 texts from social media and expressive writing were collected. The Chi-square test was used to compare the frequency of physical symptoms between depressed and undepressed patients with BC.

Impact of Sintering Aid Type and Content on the Mechanical Properties of Digital Light Processing 3D-Printed SiN Ceramics.

Digital light processing (DLP) 3D-printed Si₃N₄ ceramics, known for their exceptional performance, offer distinct advantages in meeting the high-strength and complex structural demands of industries such as aerospace, semiconductors, healthcare, automotive, energy, and machinery. However, due to Si₃N₄'s strong chemical stability, low diffusion rate, low self-sintering ability, and high melting point, achieving densification under conventional sintering conditions is challenging. As a result, sintering additives are essential to promote the sintering process, lower the sintering temperature, improve densification, and enhance performance.

Attitudes and Barriers to Patient Participation in Evidence-Based Practice From Chinese Nurses' Perspectives: A Qualitative Content Analysis.

Patient participation plays a vital role in evidence-based practice (EBP), yet its development in clinical nursing is slow. Current research has focused on identifying barriers to patient participation in everyday care, with less research on barriers to patient participation in EBP. Therefore, a questionnaire containing basic information and open-ended questions was used to explore nursing staff attitudes and barriers to patient participation in EBP.

Anisotropic hydrogel sensors with muscle-like structures based on high-absorbent alginate fibers.

Hydrogel sensors have attracted much attention as they play a critical role in health monitoring, multifunctional electronic skin, and human-machine interfaces. However, the isotropic structure makes existing hydrogel sensors exhibit isotropic sensing performance. Therefore, it is a challenge to fabricate hydrogels with human tissue-like structures to achieve anisotropic sensing performance.

Sulforaphane inhibits TGF-β-induced fibrogenesis and inflammation in human Tenon's fibroblasts.

Purpose: Subconjunctival fibrosis is the main cause of failure after glaucoma filtration surgery. We explored the effects of sulforaphane (SFN) on the conversion of human Tenon's fibroblasts (HTFs) into myofibroblasts, transforming growth factor (TGF)-β-induced contraction of collagen gel, and inflammation.

Methods: After treatment with the combination of TGF-β and SFN or TGF-β alone, primary HTFs were subjected to a three-dimensional collagen contraction experiment to examine their contractility.

Influence of campus exclusion on bullying behavior of junior high school students: role of callous-unemotional traits and family caring.

School bullying significantly impacts adolescent physical and mental development. The current study aimed to explore the effect of campus exclusion on school bullying behavior among junior high school students and the role of callous-unemotional traits and family caring. The Campus Exclusion Questionnaire, Olweus Child Bullying Questionnaire, Callous-Unemotional Trait Scale, and Family Caring Scale were completed by 705 students.

Discrete Illumination-Based Compressed Ultrafast Photography for High-Fidelity Dynamic Imaging.

Compressed ultrafast photography (CUP) can capture irreversible or difficult-to-repeat dynamic scenes at the imaging speed of more than one billion frames per second, which is obtained by compressive sensing-based image reconstruction from a compressed 2D image through the discretization of detector pixels. However, an excessively high data compression ratio in CUP severely degrades the image reconstruction quality, thereby restricting its ability to observe ultrafast dynamic scenes with complex spatial structures. To address this issue, a discrete illumination-based CUP (DI-CUP) with high fidelity is reported.

Biodegradable magnesium and zinc composite microspheres with synergistic osteogenic effect for enhanced bone regeneration.

Biodegradable polymer microspheres in bone tissue engineering have become appealing as their non-invasive advantages in irregular damage bone repair. However, current microspheres used in BTE still lack sufficient osteogenic capacity to induce effective bone regeneration. In this study, we developed osteogenic composite microspheres concurrently loaded with magnesium oxide (MgO) and zinc oxide (ZnO), both of which are osteogenic active substances, using a facile and scalable emulsification method.

Cytosolic DNA sensors activation of human astrocytes inhibits herpes simplex virus through IRF1 induction.

Introduction: While astrocytes participate in the CNS innate immunity against herpes simplex virus type 1 (HSV-1) infection, they are the major target for the virus. Therefore, it is of importance to understand the interplay between the astrocyte-mediated immunity and HSV-1 infection.

Methods: Both primary human astrocytes and the astrocyte line (U373) were used in this study.

Reporting of Ethical Considerations in Qualitative Research Utilizing Social Media Data on Public Health Care: Scoping Review.

Background: The internet community has become a significant source for researchers to conduct qualitative studies analyzing users' views, attitudes, and experiences about public health. However, few studies have assessed the ethical issues in qualitative research using social media data.

Objective: This study aims to review the reportage of ethical considerations in qualitative research utilizing social media data on public health care.

Advances in proteomics in diffuse large B‑cell lymphoma (Review).

Diffuse large B‑cell lymphoma (DLBCL) is the most common pathological type of non‑Hodgkin's lymphoma. Although the development of monoclonal antibodies, small‑molecule‑targeted drugs and novel chemotherapeutic agents, and the increased use of immunotherapy have markedly improved the outcomes of DLBCL, ~40% of patients cannot be cured following the use of standardized first‑line treatment. In addition, the specific mechanisms of drug resistance and potential factors associated with a poor prognosis in these patients remain unclear.

Transition status and influencing factors of newly graduated nurses: A descriptive survey design.

Aims: To assess the transition status of newly graduated nurses in China and identify its influencing factors.

Background: Newly graduated nurses are the indispensable part of nursing human resource. The successful transition of into clinical work is crucial for their future career development.

Pre-treatment assessment of chemotherapy for cancer patients: a multi-site evidence implementation project of 74 hospitals in China.

Background: Chemotherapy, whilst treating tumours, can also lead to numerous adverse reactions such as nausea and vomiting, fatigue and kidney toxicity, threatening the physical and mental health of patients. Simultaneously, misuse of chemotherapeutic drugs can seriously endanger patients' lives. Therefore, to maintain the safety of chemotherapy for cancer patients and to reduce the incidence of adverse reactions to chemotherapy, many guidelines state that a comprehensive assessment of the cancer patient should be conducted and documented before chemotherapy.

Semaphorin 7A impairs barrier function in cultured human corneal epithelial cells in a manner dependent on nuclear factor-kappa B.

Aim: To evaluate the role of semaphorin 7A (Sema7A) and its associated regulatory mechanisms in modulating the barrier function of cultured human corneal epithelial cells (HCEs).

Methods: Barrier models of HCEs were treated with recombinant human Sema7A at concentrations of 0, 125, 250, or 500 ng/mL for 24, 48, or 72h . Transepithelial electrical resistance (TEER) as well as Dextran-fluorescein isothiocyanate (FITC) permeability assays were conducted to assess barrier function.

The efficacy and safety of continuous intravenous infusion of rh-endostatin combined with platinum-based doublet chemotherapy for advanced non-small-cell lung cancer.

Background: Platinum-based doublet chemotherapy is commonly used in the treatment of non-small cell lung cancer (NSCLC). A growing body of evidence indicates that incorporating antiangiogenic agents into platinum-based chemotherapy may enhance the survival outcomes for NSCLC patients. However, the optimal administration protocol for intravenous recombinant human endostatin (rh-endostatin), an antiangiogenic agent, remains uncertain at present.

CDK4/6 inhibitors in drug-induced liver injury: a pharmacovigilance study of the FAERS database and analysis of the drug-gene interaction network.

Objective: The aim of this study was to investigate the potential risk of drug-induced liver injury (DILI) caused by the CDK4/6 inhibitors (CDK4/6is abemaciclib, ribociclib, and palbociclib by comprehensively analyzing the FDA Adverse Event Reporting System (FAERS) database. Moreover, potential toxicological mechanisms of CDK4/6is-related liver injury were explored via drug-gene network analysis.

Methods: In this retrospective observational study, we collected reports of DILI associated with CDK4/6i use from the FAERS dated January 2014 to March 2023.

Association between air pollution and male sexual function: A nationwide observational study in China.

This study aimed to explore the associations between air pollution and male sexual function. A total of 5047 male subjects in China were included in this study. The average air pollution exposure (PM, PM, SO, CO, NO, and O) for the preceding 1, 3, 6, and 12 months before the participants' response was assessed.

Multiple pulmonary cavities in an immunocompetent patient: a case report and literature review.

Legionella pneumonia (LP) is a relatively uncommon yet well-known type of atypical community-acquired pneumonia (CAP). It is characterized by a rapid progression to severe pneumonia and can be easily misdiagnosed. In most patients, chest computed tomography (CT) showed patchy infiltration, which may progress to lobar infiltration or even lobar consolidation.