Publications by authors named "Zihan Chu"

Article Synopsis
  • Differentiating between bipolar disorder (BD) and major depressive disorder (MDD) is difficult in clinical settings; this study examines radiomic textural features from brain MRI scans as a potential solution.
  • A total of 253 subjects (114 with BD, 139 with MDD) were analyzed using a new method to extract and combine various radiomic features along with gray matter volume data.
  • The best classification model achieved strong results, suggesting that incorporating advanced radiomic features can enhance the diagnosis of BD and MDD, although the study's limitation includes data coming from only one center without external validation.
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It is evident that sarcasm can be interpreted differently due to various factors, However, rare research was conducted to investigate the influence of national culture on sarcasm comprehension despite its valuable theoretical implication. This study used an online rating task to explore how national culture impacts the comprehension of sarcasm, focusing on the differences between Chinese and American cultural values (i.e.

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The block copolymer micelles and natural biopolymers were utilized to form layer-by-layer (LbL) films via electrostatic interaction, which were able to effectively load and controllably release favipiravir, a potential drug for the treatment of coronavirus epidemic. The LbL films demonstrated reversible swelling/shrinking behavior along with the manipulation of temperature, which could also maintain the integrity in the structure and the morphology. Due to dehydration of environmentally responsive building blocks, the drug release rate from the films was decelerated by elevating environmental temperature and ionic strength.

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Monastic houses are an essential part of the Tibetan monastic system in China. In this study, the monastic houses of Labrang in the Tibetan region of Gannan were used as the research objects. Physical parameters such as indoor temperature, humidity, and radiation temperature of the monastic houses were measured.

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Using surface-initiated atom transfer radical polymerization (ATRP), block polymers with a series of quaternization degrees were coated on the surface of silica nanocapsules (SNCs) by the "grafting-from" technique. Molnupiravir, an antiviral medicine urgently approved for the treatment of SARS-CoV-2, was encapsulated in polymer-coated SNCs and further incorporated into well-defined films with polystyrene sulfonate (PSS) homopolymers by layer-by-layer (LBL) self-assembly via electrostatic interactions. We investigated the impact of the quaternization degree of the polymers and steric hindrance of functional groups on the growth mode, swelling/deswelling transition, and drug-delivering efficiency of the obtained LBL films.

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We describe layer-by-layer (LbL) buildup and pH-responsive behavior of multilayer films of alginate/chitosan/alginate -modified silica nanocapsules (SNCs) and chitosan (CS) biopolymers via electrostatic interaction. The SNC/CS films exhibit pH-triggered swelling/deswelling transitions under physiological conditions. Fulvestrant, an FDA-approved selective estrogen receptor down-regulator agent for the treatment of breast cancer, was encapsulated in SNCs and further incorporated into the LbL films.

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