Publications by authors named "Zih-Syuan Chen"
Article Synopsis
- This study examines the impact of pre-treatment nutritional and inflammatory status on cancer outcomes, focusing on patients with locally advanced head and neck squamous cell carcinoma (LAHNSCC).
- It found that cancer patients had lower levels of certain amino acids and worse body composition compared to healthy controls, but higher levels of inflammation and malnutrition.
- The research concluded that poor nutrition and high inflammation at baseline were linked to worse survival rates, suggesting that pre-treatment assessments of nutrition and inflammation should be part of future clinical trials.
Aim: The relationship between genetic polymorphisms of the glucagon-like peptide-1 (GLP-1) receptor (GLP1R) gene and unresponsiveness to GLP-1 analogue treatment in patients with poorly controlled type 2 diabetes mellitus (DM) is unclear.
Methods: Thirty-six patients with poorly controlled type 2 DM were enrolled and they received six days of continuous subcutaneous insulin infusion for this study. After the normalization of blood glucose in the first 3 days, the patients then received a combination therapy with injections of the GLP-1 analogue, exenatide, for another 3 days.