Publications by authors named "Zige Tang"
Long Non-Coding RNA HCP5 Affects Ferroptosis in Lung Adenocarcinoma through miR-17-5p/HOXA7 Axis.
Curr Cancer Drug Targets
October 2024
Article Synopsis
- Ferroptosis, a specific type of regulated cell death linked to iron-induced damage, is relevant in lung adenocarcinoma (LUAD) and is influenced by the lncRNA HCP5, which is known to promote cancer but has an unclear role in ferroptosis.
- This study explores the HCP5/miR-17-5p/HOXA7 relationship, using cell experiments and various assays to demonstrate how HCP5 interacts with these molecules to affect cell viability and behavior in LUAD.
- Results indicate that HCP5 enhances the growth and invasiveness of lung cancer cells by modulating miR-17-5p and HOXA7, and that reducing HCP5 levels