Synopsis of recent research by authors named "Zige Li"
- Zige Li's research primarily focuses on innovative approaches to enhance bone regeneration and healing in orthopedic conditions, particularly through the application of traditional Chinese medicine, specifically the total flavonoids of Rhizoma Drynariae (TFRD).
- His studies reveal that TFRD not only promotes angiogenesis but also enhances osteogenesis by activating specific signaling pathways, namely PDGF-BB/VEGF/RUNX2/OSX, which are critical for successful bone repair in models of distraction osteogenesis.
- Additionally, Li explores the challenges associated with various treatment modalities for bone defects, evaluating techniques like the induced membrane method versus distraction osteogenesis to determine the most effective strategies for achieving optimal healing outcomes.