Optimization of enzyme-assisted microwave extraction, structural characterization, antioxidant activity and in vitro protective effect against HO-induced damage in HepG2 cells of polysaccharides from roots of Rubus crataegifolius Bunge.

In this study, an enzyme-assisted microwave extraction process was obtained by response surface method of polysaccharide from roots of Rubus crataegifolius Bunge. The optimized extraction process was as follow: enzyme dosage 2 %, enzymatic time was 3.6 h, enzymatic pH 4.

Flavonoids-rich extract from Bidens bipinnata L. protects pancreatic β-cells against oxidative stress-induced apoptosis through intrinsic and extrinsic pathways.

Ethnopharmacological Relevance: As a traditional Chinese medicinal, Bidens bipinnata L. has been used to treat many diseases with a long history in China. The anti-diabetic effects of extract from B.

Enrichment of flavonoid-rich extract from Bidens bipinnata L. by macroporous resin using response surface methodology, UHPLC-Q-TOF MS/MS-assisted characterization and comprehensive evaluation of its bioactivities by analytical hierarchy process.

The extract of Bidens bipinnata L. exhibited wide spectrum of bioactivities owing to the presence of flavonoids. In this study, a purification process was developed to enrich the flavonoid-rich extract from B.