Interplay of correlations and Majorana mode from local solution perspective.

We study the quasiparticle spectrum of a hybrid system, comprising a correlated (Anderson-type) quantum dot coupled to a topological superconducting nanowire hosting the Majorana boundary modes. From the exact solution of the low-energy effective Hamiltonian, we uncover a subtle interplay between Coulomb repulsion and the Majorana mode. Our analytical expressions show that the spectral weight of the leaking Majorana mode is sensitive to both the quantum dot energy level and the repulsive potential.

Peer-to-peer validation of Ki-67 scoring in a pathology quality circle as a tool to assess interobserver variability: are we better than we thought?

Ki-67, a nuclear protein expressed in all stages of cellular proliferation, is a valuable tool to assess tumor proliferation and has been linked to more aggressive tumor behavior. However, interlaboratory staining heterogeneity and inter-observer variability challenge its reproducibility. Round Robin tests are a suitable tool to standardize and harmonize immunohistochemical and molecular analyses in histopathology.

Quench dynamics of Fano-like resonances in the presence of the on-dot superconducting pairing.

We explore the electron dynamics of a system composed of double quantum dot embedded between metallic and superconducting leads in a "T-shape" geometry. In nanoscopic systems, where electron transfer between electrodes can be realized via different paths, interference effects play an important role. For double quantum dot system in the chosen geometry, interference of electrons transferred between electrodes via the interfacial quantum dot and electrons scattered on the side dot gives rise to Fano-like interference.

Evaluation of a tryptase depletion index for better pathologic identification of mast cell activation syndrome.

Background: Laboratory evidence supporting diagnosis of the prevalent condition of mast cell activation syndrome (MCAS) currently includes elevated levels in blood or urine of mediators relatively specific to mast cells (MCs) and/or increased numbers of MCs in luminal gastrointestinal (GI) tract tissues. However, identification of elevated mediators is technically challenging and expensive, and controversy persists regarding the normal ranges of numbers/counts of MCs in various GI tract segments, let alone challenges in determining how many of the visualized MCs are activated. To aid diagnosis of MCAS, we developed a potential new approach for the pathologist to identify the extent of GI tract MC activation easily and inexpensively.

[Cystic diseases in urology : Recommendations for patients with systemic mast cell disease].

The systemic mast cell disease (MCAD; prevalence 17%) may occur frequently in urological patients. MCAD-induced changes include cysts in all organs, also in the urogenital system. In the presence of MCAD, the surgical removal of such cysts must consider specific features of the MCAD in order to reduce surgical and complication risks.

Determinants and disparities in access to paediatricians in Poland.

Background: The purpose of this study was to identify the factors that determine the differences in the distribution and workload of paediatricians in Poland. This research, specific to conditions found within Poland, will help further advance knowledge in this area. Data were derived from the database of Statistics Poland.

[Hemoglobin drop after thrombolytic therapy in a 57-year-old stroke patient with "erosive gastritis"].

A 57-year-old woman underwent esophagogastroduodenoscopy due to a continuous drop in hemoglobin levels reaching 7.4 g/dl after treatment with intravenous thrombolytic therapy 1 week earlier because of an ischemic insult. Numerous erosive lesions were found in the gastric corpus.

Socio-economic development, level of urbanization and consumption of selected food products as factors in the prevalence of overweight and obesity among youths and young adults in Poland.

Introduction And Objective: Obesity and overweight among teenagers and young adults pose serious problems for the Polish health care system. The aim of this study was to assess the relationships between the prevalence of overweight and obesity and the level of urbanization, consumption of selected food products and socio-economic development in the provinces in Poland.

Material And Methods: The material used in this study is based on data published by the Central Statistics Office (GUS) for population, components of the Human Development Index (HDI), urbanization level (URBI), average monthly consumption of selected food products per person, and the percentage of obese and overweight people in the Polish provinces.

Anomalous Fano Resonance in Double Quantum Dot System Coupled to Superconductor.

We analyze the influence of a local pairing on the quantum interference in nanoscopic systems. As a model system we choose the double quantum dot coupled to one metallic and one superconducting electrode in the T-shape geometry. The analysis is particularly valuable for systems containing coupled objects with considerably different broadening of energy levels.

Leakage of Majorana mode into correlated quantum dot nearby its singlet-doublet crossover.

We study quasiparticle spectrum of the correlated quantum dot (QD) deposited on superconducting (SC) substrate which is side-coupled to the Rashba nanochain, hosting Majorana end modes. Ground state of an isolated QD proximitized to SC reservoirs is represented either by the singly occupied site or BCS-type superposition of the empty and doubly occupied configurations. Quantum phase transition between these distinct ground states is spectroscopically manifested by the in-gap Andreev states which cross each other at the Fermi level.

Regional differences in access to health care in Poland from the perspective of health care resources.

Objective: To examine disparities in access to the public in Poland, in association of the resources of health care, socio-economic development of Provinces and their level of urbanization.

Material And Methods: The Provinces were divided into four groups, using the quartile method, according to the urbanization and level of socio-economic development. The socio-economic development level was identified by the Human Development Index (HDI) for each Province.

Risk of solid cancer in patients with mast cell activation syndrome: Results from Germany and USA.

 It has been shown repeatedly that mast cells can promote or prevent cancer development and growth. If development and/or progression of a solid cancer is substantially influenced by mast cell activity, the frequencies of occurrence of solid cancers in patients with primary mast cells disorders would be expected to differ from the corresponding prevalence data in the general population. In fact, a recent study demonstrated that patients with systemic mastocytosis (i.

[A very rare cause of haemoptysis - coexistence of primary oncocytic adenoma of trachea with bronchial carcinoma].

History And Admission Findings: A 70-year-old man with a past history of COPD stage GOLD D with home oxygen therapy and tracheotomy due to long-term ventilation (898 hours) 6 years ago was admitted for investigation of haemoptysis during oral anticoagulation. He suffered from peripheral arterial disease (PAD) with bypass and repeated thrombectomy due to recurrent bypass caps, despite effective warfarin therapy. He had all cardiovascular risk factors.

Influence of urbanization level and Gross Domestic Product on the prevalence of adolescent obesity in Poland.

Introduction: Obesity is considered as a major disease of twenty-first century civilization. Its occurrence in Poland and worldwide has been increasing steadily for many years. Several factors play an important role in the development of overweight and obesity.

Regional diastolic and systolic function by strain rate imaging for the detection of intramural viability during dobutamine stress echocardiography in a porcine model of myocardial infarction.

The aim of this study was to evaluate diastolic and systolic strain rate measurements for differentiation of transmural/nontransmural infarction during dobutamine stress echocardiography (DSE). An ameroid constrictor was placed around the circumflex artery in 23 pigs inducing chronic vessel occlusion. Five pigs without constrictor served as controls.

[Seminoma necrosis by testicular torsion].

The coincidence of a classical scrotal testicular torsion with a scrotal tumor is a rare event. In the case described here the classical histological characteristics of a seminoma were present in addition to clear signs of testicular torsion with fibrin-containing thrombi in the intratesticular capillaries, so that the ischemia time predicted by the pathologists correlated well with the clinical data of 7.5 h for the testicular torsion estimated at the time of the intervention.

Transplantation of bone marrow-derived stem cells improves myocardial diastolic function: strain rate imaging in a model of hibernating myocardium.

Background: The aim of this study was to evaluate the cardioprotective effects of bone marrow-derived stem cells on myocardial compliance in a chronic ischemia model regarding strain rate (SR) parameters during dobutamine stress echocardiography (DSE).

Methods: Ameroid constrictors were placed around the circumflex arteries of 23 domestic pigs to induce chronic vessel occlusions. Fifteen pigs received transendocardially bone marrow derived stem cells, and 8 received placebo injections (a 0.

Intramyocardial transplantation of bone marrow-derived stem cells: ultrasonic strain rate imaging in a model of hibernating myocardium.

Background: The aim of this study was to evaluate potential cardioprotective effects of bone marrow-derived stem cells in chronic ischemic myocardium regarding strain rate parameters during dobutamine stress echocardiography.

Methods: An ameroid constrictor was placed around the circumflex artery in 23 pigs to induce hibernating myocardium. Pigs received autologous mesenchymal stem cells (auto MSCs), allogeneic MSC (allo MSC), autologous mononuclear cells (auto MNCs), or placebo injections into the ischemic region.

Diagnosis of patent foramen ovale by transesophageal echocardiography and correlation with autopsy findings.

Transesophageal echocardiography (TEE) is accepted as the method of choice for the diagnosis of the patent foramen ovale (PFO). However, direct anatomic confirmation regarding the presence or absence of a PFO on transesophageal imaging has been obtained in only a limited number of patients. Consequently, this study was performed to assess the diagnostic accuracy of contrast and color Doppler TEE for detection of a PFO by comparing the results of TEE with autopsy.

Quantitative lectin-histochemical and immunohistochemical studies on the occurrence of alpha(2,3)- and alpha(2,6)-linked sialic acid residues in colorectal carcinomas. Relation to clinicopathologic features.

Background: Enhanced sialylation has been considered important for the metastatic growth of colorectal carcinomas. Using sequence- and sialic acid-specific lectins and a monoclonal antibody, the tumor-associated expression of alpha(2,3)- and alpha(2,6)-sialylated oligosaccharides was investigated. The study was designed to examine whether a random increase of sialylation or the expression of oligosaccharides carrying distinct sialic acid residues affect the biology of colorectal carcinomas.