Publications by authors named "Zidouni N"

Background: Lung cancer is a major cause of death worldwide. However, few data on incidence, histologic types and mortality rates of lung cancer were available for Algeria.

Methods: LuCaReAl is an ongoing descriptive, non-interventional, national, multicenter, prospective and longitudinal study conducted in Algeria, among oncologists and pulmonologists in public community and university hospitals.

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Purpose: This study was performed to assess symptom variability and its impact on morning activities in stable patients with severe COPD in the Middle East and Africa (MEA) countries.

Patients And Methods: Non-interventional, cross-sectional study (NCT03425760) in patients with severe COPD (GOLD 2015, C, or D categories). Symptom variability was assessed directly by interviewing the patient and using the Global Chest Symptoms Questionnaire (GCSQ).

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Article Synopsis
  • - The study examined recent asthma control data in Algeria, comparing results with other countries in the Middle East and North Africa (MENA) to address the lack of updated information.
  • - Conducted on 984 adults with asthma, it found that only 34.6% had good asthma control, with significant factors like low education and lack of exercise contributing to poor management.
  • - Despite high specialist care involvement, the study concluded that improving healthcare training and patient education are essential to address the ongoing issues of asthma control in Algeria.
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Purpose: Common variable immunodeficiency (CVID) is the commonest symptomatic primary immunodeficiency. It is characterized by a defect of antibody production, recurrent respiratory tract infections and increased occurrence of auto-immune discords and lymphoproliferative disease.

Methods: This retrospective study was conducted on 29 patients fulfilling the classical CVID definition.

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Setting: A total of 77 health care facilities in 10 provinces.

Objective: To perform a feasibility study before the extension of the Practical Approach to Lung (PAL) health strategy.

Method: A cross-sectional study comparing before and after findings of a training course for general practitioners.

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Setting: Emergency rooms.

Objective: To assess quality of care and its determinants for asthma patients before emergency room treatment.

Design: Consecutive patients with acute severe asthma attending emergency rooms were questioned about the severity of their disease and treatment in the previous 4 weeks.

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Setting: Although there are proven risk factors related to air pollution, the prevalent situation in low-income countries is not well known.

Objective: To quantify the health impacts associated with particulate air pollution in the city of Algiers.

Design: Descriptive study to evaluate a health impact assessment (HIA) approach based on a dose-response curve from the literature.

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Setting: Seven selected out-patient clinics caring for asthma patients in Algeria, Guinea, Morocco, Syria, Turkey and Vietnam.

Design: Evaluation of treatment outcomes after one year of follow-up of a cohort of asthma patients consecutively enrolled in a prospective study evaluating routine practice.

Results: Among 310 asthma patients registered, the following outcomes were recorded after one year of follow-up: 95 (31%) successful, 61 (20%) under control, 35 (11%) failed, 116 (37%) defaulted and 3 (1%) transferred.

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Setting: Nine selected out-patient clinics caring for asthma patients in Algeria, Guinea, Ivory Coast, Kenya, Mali, Morocco, Syria, Turkey and Vietnam.

Design: Prospective enrolment of consecutive patients considered by the practitioner to have asthma with evaluation of adherence of the practitioner with recommended standard case management, including proportion of patients confirmed to have asthma, proportion in whom severity was correctly graded and proportion in whom treatment with inhaled corticosteroids corresponded to severity grade.

Results: Of 499 consecutive patients, 456 (91%) were enrolled and evaluated.

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Since the major accidents that occurred in the 1960s, air pollution has commonly been considered as a respiratory risk factor whose effects are most often studied in industrialised countries. Our aim is to show that it is now the turn of low- and middle-income countries to take this risk factor into account. After a discussion of the characteristics of air pollution, how it is diffused and the main known health effects (short- and long-term effects), we describe the specific differences between the cities in the North and the South.

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Setting: The cost and availability of the medications required for the treatment of asthma may represent potential barriers to effective management.

Method: A survey of prices and policies for components of asthma treatment in 1998, in Algeria, Burkina Faso, Ivory Coast, Guinea, Mali, Syria, Turkey and Vietnam.

Results: Medications were consistently available in only four of the eight countries studied.

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Recent WHO recommendations for the treatment of tuberculosis have emphasized the need for simplicity and standardization of short term chemotherapy regims which can be applied in all forms of tuberculosis, including both pulmonary and extrapulmonary forms. But in order for the recommended chemotherapy regimes to be effective, there is a need for precise organization. Patient care must begin with the first consultation, dosage must be adapted to patient weight, drug intake must, at least during the initial phase of treatment, be supervised and patients who are absent or irregular should be recalled, surveillance and correction of rare side effects should be recorded, global consideration of the patient's medical and social problems and laboratory (and clinical) check-ups at the end of the initial phase of treatment and again at the end of treatment.

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