The association of preconceptional folic acid supplementation with gestational age and preterm birth risk in twin pregnancies: a prospective cohort study in China.

Purpose: This study aims to explore the association of maternal preconceptional folic acid (FA) supplementation with gestational age and preterm birth in twin pregnancies, and whether the association varies by chorionicity or conception mode.

Methods: From November 2018 to December 2021, the information of FA supplementation and pregnancy outcomes were collected in twin pregnant women. The linear regression models and the logistic regression were used to test the association of preconceptional FA supplementation with gestational age at delivery and preterm birth and premature rupture of membranes (PROM).

Assessing causal relationships between gut microbiota and asthma: evidence from two sample Mendelian randomization analysis.

Background: Accumulating evidence has suggested that gut microbiota dysbiosis is commonly observed in asthmatics. However, it remains unclear whether dysbiosis is a cause or consequence of asthma. We aimed to examine the genetic causal relationships of gut microbiota with asthma and its three phenotypes, including adult-onset asthma, childhood-onset asthma, and moderate-severe asthma.

The associations of chronotype and social jetlag with prosocial behavior problems among Chinese adolescents.

Potential relevance between the circadian rhythm and behavioral health has got raising attention in recent years. This study aimed to examine chronotype, social jetlag and their associations with prosocial behavior problems among Chinese adolescents. A total of 4,666 middle school students aged 12-18 years were enrolled in study.

Relationships between Sleep Duration, Timing, Consistency, and Chronotype with Myopia among School-Aged Children.

Background: The role of sleep in childhood myopia has been a research focus; however, the existing evidence is conflicting on sleep duration and timing, and as yet, no studies involve sleep consistency and chronotype. This study is done to make multiple-perspective analyses on the associations between sleep variables and myopia.

Methods: A population-based cross-sectional study was conducted in Shanghai, China, which included 10,142 school-aged children (7-12 years old, 53.

Exploring genetic association of insomnia with allergic disease and asthma: a bidirectional Mendelian randomization study.

Background: Insomnia is highly prevalent among patients with allergic disease and asthma; however, few studies have investigated their causal relationship. We aim to explore the causal association between insomnia and allergic disease/asthma by performing bidirectional Mendelian randomization (MR) study.

Methods: Instrumental variables were constructed using single nucleotide polymorphisms (SNPs).

Sex-specific association of sleep duration with subclinical indicators of metabolic diseases among asymptomatic adults.

Background: Accumulating evidence suggests sleep duration may be involved in metabolic regulation. However, studies regarding the association with the early stage of the metabolic disease are limited, and the findings were inconsistent.

Methods: A study among 4922 asymptomatic adults was conducted based on a Chinese national survey in 2009.

Trends of central obesity and associations with nutrients intake and daily behaviors among women of childbearing age in China.

Background: Obesity among women of childbearing age has becoming an important public health concern. We aimed to describe the trends of central obesity among Chinese women of childbearing age from 2004 to 2011 and to examine its associations with nutrients intake and daily behaviors.

Methods: Longitudinal data were derived from the China Health and Nutrition Survey.

The Associations of Trajectory of Sleep Duration and Inflammation with Hypertension: A Longitudinal Study in China.

Background: Existing evidence suggested that sleep duration may be involved in hypertension; however, the conclusions were still controversial. This study aimed to examine the association of longitudinal trajectory of sleep duration with hypertension and to explore the role of the inflammation in such associations.

Methods: A total of 3178 subjects over 30 years of age without hypertension were enrolled in 2004, and they were followed until 2009.

How to Understand "Herd Immunity" in COVID-19 Pandemic.

The COVID-19 pandemic has been a global threat. Through rapid and effective surveillance and control, the newly confirmed patients have been fluctuated at a very low level and imported case explained most of them through March, 2020 to the present, indicating China's response has achieved a stage victory. By contrast, the epidemic of COVID-19 in other countries out of China is bursting.

Gender-Specific Longitudinal Association of Sleep Duration with Blood Pressure among Children: Evidence from CHNS 2004-2015.

Purpose: We conducted this study to add the evidence regarding the gender-specific association between sleep duration and blood pressure (BP) in children.

Methods: A secondary analysis was performed among 1000 children aged 7-13 years, who had at least two rounds of survey records in China Health and Nutrition Survey through 2004-2015. Generalized estimating equation was used to explore the gender-specific association of sleep duration with BP.