Based on the surface plasmon resonance of metal and anti-resonant principles of hole-core microstructure optical fiber (MSF), in this Letter, we demonstrate a MSF microfluidic sensor that combines silver film and hole-core MSF to achieve the sensitive real-time monitoring of refractive indices and components. The large hole core is a common channel for guiding light and flowing measured liquid. Because of the interaction between light and continuous flow measured liquid, the component and refractive indices can be simultaneously monitored by the characteristic absorption wavelength and the surface plasmon resonant peak position, respectively.
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