Transvaginal double-layer parallel in-situ suturing for early complex vesicovaginal fistula repair: Case report.

Rationale: Complex vesicovaginal fistulas (VVFs) with large defects pose significant surgical challenges. Traditional repair methods often require extensive tissue separation and multilayer suturing, risking local blood supply and healing. This study introduces a novel modified transvaginal repair technique that simplifies the procedure while preserving tissue vascularity.

Migration of an intrauterine device to the posterior urethra with stone formation: a case report.

Migration of an intrauterine device (IUD) to the posterior urethra with stone formation has not been previously reported in the literature. A 42-year-old female patient presented to the gynecology clinic with a complaint of "discovered vaginal mass for 2 years, with growth for 5 days." She was referred to urology on suspicion of IUD migration to the bladder.

Apelin ameliorates sepsis-induced myocardial dysfunction via inhibition of NLRP3-mediated pyroptosis of cardiomyocytes.

Sepsis-induced myocardial dysfunction (SMD) is the major cause of death in sepsis. Nucleotide-binding oligomerization domain-like receptor family pyrin domain containing 3 (NLRP3)-mediated pyroptosis contributes to the occurrence and development of SMD. Although Apelin confers direct protection against SMD, the potential mechanisms remain unclear.

Double gains: Boosting crop productivity and reducing carbon footprints through maize-legume intercropping in the Yellow River Delta, China.

The increasing demand for environmentally friendly agricultural practices has driven the need for diversified crop cultivation to optimize crop productivity while minimizing carbon footprints (CFs). However, the impacts of crop diversification on crop production and environmental benefits are still poorly understood. In this study, conducted at two sites in the Yellow River Delta, China, we investigated the effects of legume intercropping, specifically maize/soybean (M/S) and maize/peanut (M/P) systems, on crop productivity, economic return, ecosystem economic budget (NEEB), CF, and carbon sustainability index (CSI) in comparison to conventional monocrops.

Effect of medical innovation policies on the prevention and control of the COVID-19 and the impact of the "Belt and Road" economy.

With the spread of the COVID-19, it is urgent for everyone to protect themselves. The introduction of the medical innovation policy has also brought certain effects to the prevention and control of the COVID-19. The specific effect will be reflected in the following research.

N-acetylcysteine improves diabetic associated erectile dysfunction in streptozotocin-induced diabetic mice by inhibiting oxidative stress.

Oxidative stress appears to play a role in the pathogenesis of diabetes mellitus erectile dysfunction (DMED). This study aimed to investigate the effect of N-acetylcysteine (NAC) on DMED in streptozotocin-induced diabetic mice and to explore potential mechanisms. In the present study, we show that an erectile dysfunction is present in the streptozotocin-induced mouse model of diabetes as indicated by decreases in intracavernous pressure responses to electro-stimulation as well as from results of the apomorphine test of erectile function.

High-Brightness Perovskite Microcrystalline Light-Emitting Diodes.

Here a high-brightness perovskite microcrystalline light-emitting diode (LED) is reported, in which the perovskite microcrystals were grown directly on the conductive substrate and a simple metal-insulator-semiconductor structure was adopted. A peak external quantum efficiency of 0.46% was obtained, which is high for perovskite microcrystalline LEDs.

Give priority to abiotic factor of phosphate additives for pig manure composting to reduce heavy metal risk rather than bacterial contribution.

Phosphate additives especially superphosphate can reduce nitrogen loss, and increase phosphorus availability in composting. This study investigated the changes of different heavy metals fractions and their relationship with bacterial community and abiotic factors during pig manure composting with adding equimolar HPO, HSO and KHPO. Results showed that both acidic and alkaline labile phosphate increased the potential ecological risk of heavy metals compared to control, but KHPO decreased the accumulation of exchangeable Zn and Mn by 12% and 15% than that with HPO and HSO addition.

Generation of an iPSC line (HRMSDUi001-A) from an azoospermic patient with 45,XY,der(13;14)(q10;q10) karyotype.

Robertsonian translocation between chromosomes 13 and 14 is reported to be a cause of male infertility. Here, we established an iPSC line (HRMSDUi001-A) from an azoospermic patient with 45,XY,der(13;14)(q10;q10) karyotype. Peripheral blood mononuclear cells were reprogrammed to generate hiPSCs by non-integrating delivery of OCT4, SOX2, KFL4 and MYC.

[Expression of G9a in breast cancer and its effect on proliferation of breast cancer cells ].

Objective: To study the expression of G9a in human breast cancer, its association with the clinicopathological characteristics of breast cancer, and its effect on the proliferation of breast cancer cells.

Methods: A total of 122 specimens of breast cancer tissues and 61 adjacent normal tissues resected between October, 2016 and October, 2017 were obtained from the Tissue Bank of Ningxia Medical University General Hospital. Immunohistochemistry and real-time PCR were used to detect the expression of G9a in the breast cancer tissues.