Short-Term Exposure of Bisphenol A Deteriorates the Quality of Rabbit Milk by Impairing Milk Fat Synthesis.

This study aimed to investigate the effects of short-term exposure of Bisphenol A (BPA) on the growth and lactation performance, blood parameters, and milk composition of lactating rabbits and explore its potential molecular mechanisms. Eight lactating rabbits with similar body weight were selected and randomly divided into the experimental group (BPA) and the control group (Ctrl). The group BPA was orally administered 80 mg/kg/day BPA on the 15th day postpartum, while the group Ctrl received a corresponding volume of vehicle.

Graphene-wrapped yolk-shell of silica-cobalt oxide as high-performing anode for lithium-ion batteries.

Silica (SiO) shows promise as anode material for lithium-ion batteries due to its low cost, comparable lithium storage discharge potential and high theoretical capacity (approximately 1961 mA h g). However, it is plagued by issues of low electrochemical activity, low conductivity and severe volume expansion. To address these challenges, we initially coat SiO with CoO, followed by introducing SiO@CoO into graphene sheets to fabricate an anode composite material (SiO@CoO/GS) with uniformly dispersed particles and a 3D graphene wrapped yolk-shell structure.

Engineering a superionic conductor surface enables fast Na transport kinetics for high-stable layered oxide cathode.

Unstable cathode/electrolyte interphase and severe interfacial side reaction have long been identified as the main cause for the failure of layered oxide cathode during fast charging and long-term cycling for rechargeable sodium-ion batteries. Here, we report a superionic conductor (NaV(PO), NVP) bonding surface strategy for O3-type layered NaNiFeMnO (NFM) cathode to suppress electrolyte corrosion and near-surface structure deconstruction, especially at high operating potential. The strong bonding affinity at the NVP/NFM contact interface stabilizes the crystal structure by inhibiting surface parasitic reactions and transition metal dissolution, thus significantly improving the phase change reversibility at high desodiation state and prolonging the lifespan of NFM cathode.

Zearalenone triggers programmed cell death and impairs milk fat synthesis via the AKT-mTOR-PPARγ-ACSL4 pathway in bovine mammary epithelial cells.

Zearalenone (ZEN), a mycotoxin from Fusarium fungi, impairs fertility and milk production in female animals; however, the mechanisms remain poorly understood. Using the bovine mammary epithelial cells (MAC-T) as the model, this study investigated the impacts of ZEN on programmed cell death (PCD) and milk fat synthesis and explored the underlying mechanism. We found that 10 ng/mL prolactin (PRL) notably enhanced the differentiation of MAC-T cells, promoting the expression of genes related to the synthesis of milk fat, protein, and lactose.

Minimizing Undesired Side Reactions Induced by Nanoscale Conductive Carbon Enables Stable Cycling of Semi-Solid Li-Ion Full Batteries.

Semi-solid lithium-ion batteries (SSLIBs) based on "slurry-like" electrodes hold great promise to enable low-cost and sustainable energy storage. However, the development of the SSLIBs has long been hindered by the lack of high-performance anodes. Here the origin of low initial Coulombic efficiency (iCE, typically <60%) is elucidated in the graphite-based semi-solid anodes (in the non-flowing mode) and develop rational strategies to minimize the irreversible capacity loss.

Comprehensive cognition of yak () gene and its anti-ferroptosis role in bisphenol A-induced fetal fibroblast model.

Apoptosis-inducing factor mitochondrion-associated 2 () has been identified as a gene with anti-ferroptosis properties. To explore whether exerts anti-ferroptosis role in yaks (), we cloned yak gene and analyzed its biological characteristics. The coding region of had 1122 bp and encoded 373 amino acids, which was conserved in mammals.

Synergistic interface and structural engineering for high initial coulombic efficiency and stable sodium storage in metal sulfides.

Transition metal sulfides (TMS) have gained significant attention as potential anode materials for sodium ion batteries (SIBs) due to their high theoretical capacity and abundance in nature. Nevertheless, their practical use has been impeded by challenges such as large volume changes, unstable solid electrolyte interphase (SEI), and low initial coulombic efficiency (ICE). To address these issues and achieve both long-term cycling stability and high ICE simultaneously, we present a novel approach involving surface engineering, termed as the "dual-polar confinement" strategy, combined with interface engineering to enhance the electrochemical performance of TMS.

Jiawei Yanghe Decoction attenuate allergic airway inflammation by suppressing group 2 innate lymphoid cells responses.

Ethnopharmacological Relevance: Jiawei Yanghe Decoction (JWYHD) is modified Yanghe Decoction (YHD). YHD historically utilized as a potent medicinal solution for addressing chronic inflammatory conditions, holds promising therapeutic potential in the treatment of asthma. However, the mechanisms underlying JWYHD's effects on allergic asthma remain unclear.

Comparison of survival benefit and safety between surgery following conversion therapy versus surgery alone in patients with surgically resectable hepatocellular carcinoma at CNLC IIb/IIIa stage: a propensity score matching study.

Objective: The objective of this study is to evaluate and compare the survival benefit and safety of surgery following conversion therapy versus surgery alone in patients diagnosed with surgically resectable hepatocellular carcinoma (HCC) at China Liver Cancer Staging (CNLC) IIb/IIIa stage.

Methods: A total of 95 patients diagnosed with surgically resectable CNLC IIb/IIIa HCC were retrospectively enrolled in our study from November 2018 to December 2022. Among them, 30 patients underwent conversion therapy followed by hepatectomy, while the remaining 65 received surgery alone.

Cloning and Characterization of Yak Gene and Its Functional Studies in a Bisphenol S-Induced Ferroptosis Model of Fetal Fibroblasts.

Dihydroorotate dehydrogenase (DHODH) is a rate-limiting enzyme of biosynthesis of pyrimidine. Although the involvement of DHODH in resisting ferroptosis has been successively reported in recent years, which greatly advanced the understanding of the mechanism of programmed cell death (PCD), the genetic sequence of the yak gene and its roles in ferroptosis are still unknown. For this purpose, we firstly cloned the coding region sequence of (1188 bp) from yak liver and conducted a characterization analysis of its predictive protein that consists of 395 amino acids.

β-Nicotinamide Mononucleotide Alleviates Hydrogen Peroxide-Induced Cell Cycle Arrest and Death in Ovarian Granulosa Cells.

Maintaining normal functions of ovarian granulosa cells (GCs) is essential for oocyte development and maturation. The dysfunction of GCs impairs nutrition supply and estrogen secretion by follicles, thus negatively affecting the breeding capacity of farm animals. Impaired GCs is generally associated with declines in Nicotinamide adenine dinucleotide (NAD) levels, which triggers un-controlled oxidative stress, and the oxidative stress, thus, attack the subcellular structures and cause cell damage.

Stable Operation Induced by Plastic Crystal Electrolyte Used in Ni-Rich NMC811 Cathodes for Li-Ion Batteries.

The LiNiMnCoO (NMC811) cathode material has been of significant consideration owing to its high energy density for Li-ion batteries. However, the poor cycling stability in a carbonate electrolyte limits its further development. In this work, we report the excellent electrochemical performance of the NMC811 cathode using a rational electrolyte based on organic ionic plastic crystal -ethyl--methyl pyrrolidinium bis(fluorosulfonyl)imide Cmpyr[FSI], with the addition of (1:1 mol) LiFSI salt.

Whole-Voltage-Range Solid-Solution Reaction in Layered Oxide Cathode of Sodium-Ion Batteries.

Layered manganese-based oxides (LMOs) are promising cathode materials for sodium-ion batteries (SIBs) due to their versatile structures. However, the Jahn-Teller effect of Mn induces severe distortion of MnO octahedra, and the resultant low symmetry is responsible for the gliding of MnO layers and then inferior multiple-phase transitions upon Na extraction/insertion. Here, hexagonal P2-Na Li Mn Ti O is synthesized through the incorporation of Li and Ti into the distorted orthorhombic P'2-Na MnO to function as a phase-transition-free oxide cathode.

Elucidation of the underlying mechanism of Hua-ban decoction in alleviating acute lung injury by an integrative approach of network pharmacology and experimental verification.

The pathogenic hyper-inflammatory response has been regarded as the major cause of the severity and death related to acute lung injury (ALI). Hua-ban decoction (HBD) is a classical prescription in traditional Chinese medicine (TCM). It has been extensively used to treat inflammatory diseases; however, its bioactive components and therapeutic mechanisms remain unclear.

Ultrafast Charge-Discharge Capable and Long-Life Na Mn Zr V(PO ) /C Cathode Material for Advanced Sodium-Ion Batteries.

Na MnV(PO ) /C (NMVP) has been considered an attractive cathode for sodium-ion batteries with higher working voltage and lower cost than Na V (PO ) /C. However, the poor intrinsic electronic conductivity and Jahn-Teller distortion caused by Mn inhibit its practical application. In this work, the remarkable effects of Zr-substitution on prompting electronic and Na-ion conductivity and also structural stabilization are reported.

Achieving Ultra-Stable All-Solid-State Sodium Metal Batteries with Anion-Trapping 3D Fiber Network Enhanced Polymer Electrolyte.

All-solid-state sodium metal batteries paired with solid polymer electrolytes (SPEs) are considered a promising candidate for high energy-density, low-cost, and high-safety energy storage systems. However, the low ionic conductivity and inferior interfacial stability with Na metal anode of SPEs severely hinder their practical applications. Herein, an anion-trapping 3D fiber network enhanced polymer electrolyte (ATFPE) is developed by infusing poly(ethylene oxide) matrix into an electrostatic spun fiber framework loading with an orderly arranged metal-organic framework (MOF).

Prussian blue/RGO with less coordinated water as superior cathode material for sodium-ion batteries.

A micro-cubic Prussian blue (PB) with less coordinated water is first developed by electron exchange between graphene oxide and PB. The obtained reduced graphene oxide-PB composite exhibited increased redox reactions of the Fe sites and delivered ultrahigh specific capacity of 163.3 mA h g (30 mA g) as well as excellent cycle stability as a cathode in sodium-ion batteries.

Retraction: Prussian blue without coordinated water as a superior cathode for sodium-ion batteries.

Retraction of 'Prussian blue without coordinated water as a superior cathode for sodium-ion batteries' by Dezhi Yang , , 2015, , 8181-8184, https://doi.org/10.1039/C5CC01180A.

Elucidating the Synergic Effect in Nanoscale MoS /TiO Heterointerface for Na-Ion Storage.

Interface engineering in electrode materials is an attractive strategy for enhancing charge storage, enabling fast kinetics, and improving cycling stability for energy storage systems. Nevertheless, the performance improvement is usually ambiguously ascribed to the "synergetic effect", the fundamental understanding toward the effect of the interface at molecular level in composite materials remains elusive. In this work, a well-defined nanoscale MoS /TiO interface is rationally designed by immobilizing TiO nanocrystals on MoS nanosheets.

A High-Rate, Durable Cathode for Sodium-Ion Batteries: Sb-Doped O3-Type Ni/Mn-Based Layered Oxides.

O3-Type layered oxides are widely studied as cathodes for sodium-ion batteries (SIBs) due to their high theoretical capacities. However, their rate capability and durability are limited by tortuous Na diffusion channels and complicated phase evolution during Na extraction/insertion. Here we report our findings in unravelling the mechanism for dramatically enhancing the stability and rate capability of O3-NaNiMnSbO (NaNMS) by substitutional Sb doping, which can alter the coordination environment and chemical bonds of the transition metal (TM) ions in the structure, resulting in a more stable structure with wider Na transport channels.