Publications by authors named "Zi-yuan Liu"

Remote sensing indices have been widely used to monitor the vegetation growth dynamics induced by climate change and human activities, and yet the consistency of the vegetation dynamics revealed by different remote sensing indices in mountains is unclear. Using Nepal as a case study, this study explored the spatial-termporal consistencies of the three widely-used remote sensing indices (i.e.

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Article Synopsis
  • Long non-coding RNAs (lncRNAs) are over 200 nucleotides long and have been found to play a significant role in cancer by influencing processes like cell death, growth, and the spread of cancer cells.
  • Research has shown that autophagy, the body's way of removing damaged cells and proteins, can have both protective and harmful effects in cancer scenarios, particularly when lncRNA expression is not regulated properly.
  • The manuscript emphasizes the need to understand how lncRNAs interact with autophagy, as this relationship could have important implications for cancer treatment and research.
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Background: During cataract phacoemulsification surgery, an Intrepid® balanced (IB) tip can achieve a larger amplitude, which may lead to higher energy efficiency than a Kelman (K) tip when paired with a torsional phaco platform. In this retrospective cohort study, we compared their energy efficiency and damage to the cornea under a new energy setting.

Methods: The medical records of 104 eyes of 79 patients were reviewed, with 47 eyes belonging to the IB group and 57 eyes belonging to the K group.

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Objective: To investigate the predictors of clinical outcomes in unresponsive patients with acquired brain injuries.

Methods: Patients with coma or disorders of consciousness were enrolled from August 2019 to March 2021. A retrospective analysis of demographics, etiology, clinical score, diagnosis, electroencephalography (EEG), and event-related potential (ERP) data from 1 week to 2 months after coma onset was conducted.

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Strongly affecting human and animal physiology, sounds and vibration are critical environmental factors whose complex role in behavioral and brain functions necessitates further clinical and experimental studies. Zebrafish are a promising model organism for neuroscience research, including probing the contribution of auditory and vibration stimuli to neurobehavioral processes. Here, we summarize mounting evidence on the role of sound and vibration in zebrafish behavior and brain function, and outline future directions of translational research in this field.

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We assessed the clinical significance of mismatch negativity (MMN) in predicting the awakening of comatose patients with severe brain injury. The clinical data of patients with severe brain injury, admitted to the neurosurgical intensive care unit of Xiangya Hospital of Central South University from July 2018 to March 2020, who underwent auditory MMN examinations within 28 days after coma onset, were reviewed. Correlations between clinical factors and prognosis [Glasgow Outcome Scale (GCS) for 3 mo] were analyzed.

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Purpose: Low-velocity penetrating brain injury (LVPBI) caused by foreign bodies can pose life-threatening emergencies. Their complexity and lack of validated classification data have prevented standardization of clinical management. We aimed to compare the trans-base and trans-vault phenotypes of LVPBI to help provide guidance for clinical decision-making of such injury type.

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Background: Long noncoding RNAs (lncRNAs) are essential modulators of cancers initiation and progression via regulating gene expression and biological behaviors. LncRNA SAMD12-AS1 has been validated to promote the progression of several cancers, while its role in gastric cancer (GC) remains unclear. This study aims to explore the role of LncRNA SAMD12-AS1 in GC.

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Aim: To investigate the phototoxic effect of long-term excessive narrow-band blue light in staurosporine-induced differentiated retinal ganglion cells-5 (SSRGC-5).

Methods: SSRGC-5 cells were divided into two groups, blue light group (BL group) and control group. Cell viability was assessed by using CCK-8 assay.

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Stress is a common trigger of stress-related illnesses, such as anxiety, phobias, depression and post-traumatic stress disorder (PTSD). Various animal models successfully reproduce core behaviors of these clinical conditions. Here, we develop a novel zebrafish model of stress (potentially relevant to human stress-related disorders), based on delayed persistent behavioral, endocrine and genomic responses to an acute severe 'combined' stressor.

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Kava kava (Piper methysticum) is a medicinal plant containing kavalactones that exert potent sedative, analgesic and anti-stress action. However, their pharmacological effects and molecular targets remain poorly understood. The zebrafish (Danio rerio) has recently emerged as a powerful new model organism for neuroscience research and drug discovery.

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Chorea-acanthocytosis (ChAc) is the most common subtype of neuroacanthocytosis syndrome, characterized by the presence of acanthocytes and neurological disorders. It is thought to be caused by VPS13A mutations. Characteristic movement disorders in ChAc is choreiform movements affecting both trunk and extremities and prominent orolingual dyskinesia is pathognomonic.

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Two novel hexanuclear Dy complexes with polyhydroxy Schiff-base ligands, [Dy(L)(μ-OH)(MeOH)]Cl·2MeOH·2MeCN (1) and [Dy(HL)(μ-OH)(μ-OCH)(piv)(MeOH)] (2) (HL = ,'-bis(3-methoxysalicylidene)(propylene-2-ol)-1,3-diamine, HL = 2,3-dihydroxypropylimino)methyl)-6-methoxyphenol, piv = pivalate), have been prepared under solvothermal conditions and structurally characterized by single-crystal X-ray diffraction, elemental analyses, thermal analyses, and IR spectroscopy. Each of the hexanuclear complexes is constructed with Dy triangular motifs as building blocks, and the six Dy ions are arranged in a chair-shaped conformation. Variable-temperature magnetic susceptibility measurements in the temperature range of 2-300 K indicate dominant ferromagnetic exchange interactions between the Dy ions in the complexes.

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Objective: To investigate the status of pubertal development in children born with assisted reproductive technology (ART).

Methods: A retrospective analysis was performed on the pubertal development data of children born with ART in Peking University Third Hospital from 1994 to 2003 (ART group). The data in the cross-sectional study "Reports on the Physical Fitness and Health Research of Chinese School Students in 2010" were used as a control.

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Objective To explore the efficacy of target positioning by preoperative CT/MRI image fusion technique in deep brain stimulation.Methods We retrospectively analyzed the clinical data and images of 79 cases (68 with Parkinson's disease, 11 with dystonia) who received preoperative CT/MRI image fusion in target positioning of subthalamic nucleus in deep brain stimulation. Deviation of implanted electrodes from the target nucleus of each patient were measured.

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Article Synopsis
  • Esophageal squamous cell carcinoma (ESCC) is a highly lethal cancer, showing a significant number of mutations, averaging 82 non-silent mutations per tumor across the studied samples.
  • The mutational profile is similar to squamous cell carcinomas in other areas but differs from esophageal adenocarcinoma, with 99% of cases showing mutations in critical genes regulating the cell cycle and apoptosis, particularly TP53 and CCND1.
  • Key mutations in histone modifier genes and dysregulation of the Hippo and Notch pathways suggest important prognostic implications, with specific mutations linked to poorer survival rates in patients.
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Objective: To determine the dry eye awareness in the populations visiting general eye clinic.

Methods: This was a cross-sectional study. A questionnaire about dry eye was designed and administrated to Peking University Third Hospital General Eye Clinic patients (n = 804) from June 2010 to June 2011.

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