Publications by authors named "Zi-shu Guan"
Article Synopsis
- This study examined how common carbapenem-resistant Enterobacterales (CRE) infections and colonizations are in intensive care unit (ICU) patients and what factors contribute to their presence at admission and during the hospital stay.
- Conducted across 24 ICUs in Anhui, China, the research involved screening patients and applying statistical analysis to identify risk factors linked to CRE colonization/infection.
- Findings revealed that 5.9% of patients had CRE at admission and 8.5% acquired it during their ICU stay, with several identified risk factors including prior hospital transfers, recent antibiotic exposure, and prolonged ICU stays.
Background: The primary aim of this study is to measure the JAK-STAT signaling in HBV infected peripheral blood mononuclear cells (PBMCs) stimulated by IFN-α and 3-TC and explore the influence of HBV to the JAKSTAT signaling pathways.
Methods: PBMCs were separated from healthy volunteers and patients who had not received any treatment with chronic hepatitis B. PBMCs were divided into the control group, IFN-α stimulation group, Lamivudine stimulation group, and combined treatment group.
Background: Quantitative polymerase chain reaction (qPCR) analysis is a precise and effective method for the study of mRNA expression throughout the field of peripheral blood mononuclear cell (PBMC) research. However, the use of suitable reference genes for data normalization is critical to obtain meaningful and reproducible results. The present study aimed to identify the greatest reference genes for further research in PBMC of Chronic Hepatitis B (CHB) patients.
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