[Polymorphisms within the interferon-Gamma receptor associated with systemic lupus erythematosus].

Objective: To assess the association between polymorphisms within the interferon-Gamma receptor gene(IFN-GammaR) and systemic lupus erythematosus (SLE) in Chinese people.

Methods: The IFN-GammaR genotypes of 94 SLE patients and 80 healthy subjects were examined by the reverse transcription-polymerase chain reaction (RT-PCR)-single-strand conformation polymorphism (SSCP) method, RT-PCR-restriction fragment length polymorphism (RFLP) method and DNA sequencing.

Results: There was no statistically significant difference in the IFN-GammaR genotype frequencies between the two groups.