Prototypical Graph Contrastive Learning.

Graph-level representations are critical in various real-world applications, such as predicting the properties of molecules. However, in practice, precise graph annotations are generally very expensive and time-consuming. To address this issue, graph contrastive learning constructs an instance discrimination task, which pulls together positive pairs (augmentation pairs of the same graph) and pushes away negative pairs (augmentation pairs of different graphs) for unsupervised representation learning.

-Butylhydroperoxide induces apoptosis in RAW264.7 macrophages a mitochondria-mediated signaling pathway.

Macrophage apoptosis occurs throughout all stages of atherosclerosis, mainly induced by oxidized low density lipoproteins (Ox LDLs), leading to the formation of necrotic cores. Nevertheless, the mechanism of macrophage apoptosis induced by Ox LDLs is not yet clearly understood. In this study, a model of RAW264.