[Bioinformatics Analysis on Key Genes and Immune Infiltration of Osteosarcoma].

Objective To screen the potential key genes of osteosarcoma by bioinformatics methods and analyze their immune infiltration patterns. Methods The gene expression profiles GSE16088 and GSE12865 associated with osteosarcoma were obtained from the Gene Expression Omnibus(GEO),and the differentially expressed genes(DEGs)related to osteosarcoma were screened by bioinformatics tools.Gene Ontology(GO)annotation,Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway enrichment,and analysis of immune cell infiltration were then carried out for the DEGs.

[Cancer incidence and mortality in Guangzhou City from 2000 to 2002].

Background & Objective: Population-based cancer registration has never been carried out before in Guangzhou. This study was to analyze the cancer incidence and mortality in Guangzhou and to provide references for prevention and treatment of cancer.

Methods: Data of cancer incidence and mortality during 2000--2002 were collected from Guangzhou Population-based Cancer Registry.