Objective: To observe the therapeutic effect between acupuncture combined with medication and simple medication on migraine and cerebral hemodynamics.
Methods: A total of 120 patients with migraine were randomized into an acupuncture plus medication group (60 cases, 3 cases dropped off) and a medication group (60 cases, 6 cases dropped off). In the medication group, flunarizine hydrochloride capsule was given orally before sleep, 10 mg a day.
Objective: To observe the difference of therapeutic effect between hysteretic acupuncture and Celecoxib capsules for knee osteoarthritis(KOA), and to investigate their effects on levels of interleukin 6(IL-6) and tumor necrosis factor α(TNF-α) in articular fluid.
Methods: Seventy-two patients with KOA were randomly divided into hysteretic acupuncture and me-dication groups, with 36 cases in each group. The patients of the hysteretic acupuncture group received hysteretic acupuncture stimulation at Dubi (ST35), Neixiyan (EX-LE4), Zusanli (ST36), Yanglingquan (GB34), Yinlingquan (SP9), Xuehai (SP10), Liangqiu (ST34) and Heding (EX-LE2) as the main acupoints for 30 min once daily.
Objective: To investigate the clinical effect of thunder-fire moxibustion combined with electroacupuncture in the treatment of cold-dampness knee osteoarthritis.
Methods: A total of 72 patients with cold-dampness knee osteoarthritis were randomly divided into observation group and control group according to the random numbers generated by computer software, with 36 patients in each group. For the observation group, electroacupuncture was performed at the main acupoints of Dubi (ST35), Neixiyan (EX-LE4), Zusanli (ST36), Yanglingquan (GB34), Yinlingquan (SP9), Xuehai (SP10), Liangqiu (ST34), and Heding (EX-LE2) once a day, with a needle retaining time of 30 min, and thunder-fire moxibustion was performed at Shenque (CV8) and Guanyuan (CV4) in the form of suspended moxibustion once a day, with 30 min each time.
Zhongguo Shi Yan Xue Ye Xue Za Zhi
August 2015
Objective: To explore the expression of insulin-like growth factor binding protein 3 (IGFBP3) in acute myeloid leukemia and its clinical significance.
Methods: Using GAPDH as internal reference, IGFBP3 gene expression was detected in the bone marrow mononuclear cells of 43 de novo AML patients, 36 patients with complete remission (CR) and 28 cases of controls by using SYBR-Green I real-time quantitative PCR, the differences of gene expression between the three groups were compared.
Results: IGFBP3 gene expression level in the de novo group were lower than that in CR group and control group (P < 0.
Zhongguo Shi Yan Xue Ye Xue Za Zhi
February 2015
Objective: The reduced expression or expression deletion of LIM domain-containing protein 1(LIMD1) gene associates with the occurrence of various solid tumors, while its role in adult acute leukemia (AL) has been rarely reported, this study was to detect LIMD1 expression in adult patients with AL and to evaluate its correlation with the different clinical and laboratorial data.
Methods: The expression levels of LIMD1 were determined by real-time quantitative PCR (RT-qPCR), LIMD1 transcripts were measured by using a relative quantification with GAPDH as a housekeeping gene, and the relationship between its expression levels and clinical parameters (sex, age, subtype, leukocyte count, leukemic blasts) was investigated by statistical analysis.
Results: The LIMD1 expression was reduced in de novo AL patients as compared with normal controls and complete remission patients(P < 0.