Publications by authors named "Zi-Lin Cheng"
Genomics-Microbiome Based Assessment of Bidirectional Causality Between Gut Microbiota and Psoriasis.
Clin Cosmet Investig Dermatol
February 2024
Article Synopsis
- - Traditional studies suggest a link between gut microbiota and psoriasis, but evidence of a mutual relationship is lacking, limiting understanding of how they interact.
- - The study utilized Mendelian randomization with extensive datasets to explore the bidirectional relationship, discovering five bacterial genera positively related to psoriasis and four negatively affected by it.
- - Findings indicate a complex bidirectional influence where psoriasis affects gut microbiota and vice versa, challenging previous observational studies by revealing different bacterial genera involved.
Successful Treatment of Psoriasis Combined with Bullous Pemphigoid with Dupilumab: A Case Report.
Clin Cosmet Investig Dermatol
June 2023
Psoriasis is an immune-mediated chronic inflammatory disease that can be combined with complications such as diabetes, cardiovascular disease, obesity, and kidney disease. The comorbidity of psoriasis with autoimmune bullous diseases (AIBD) has been reported previously in several cases, the most frequent of which is bullous pemphigoid (BP). The underlying mechanisms of psoriasis with BP are not clear and there are no uniform treatment criteria.
View Article and Find Full Text PDFBackground: Fibroblast growth factor 21 (FGF21), an FGF family member, is an atypical hormone and pro-longevity factor.
Methods: To better understand of the effects of exogenous administration of FGF21 on lifespan and stress tolerance, and the underlying molecular basis, we used the silkworm, , as an experimental animal model to evaluate FGF21's pharmaceutical effects.
Results: Lifespan was significantly prolonged in female silkworms with FGF21 replenishment, whereas no effect was observed in the male silkworms.