Publications by authors named "Zi-Li Zhou"

Article Synopsis
  • * Among 704 yeast isolates, the most common pathogenic species from farmers were Candida albicans and C. parapsilosis, while C. tropicalis was prevalent in environmental samples, with a notable fluconazole resistance rate.
  • * The resistance of C. tropicalis to fluconazole was linked to resistance to certain agricultural azole fungicides, and gene mutations were identified as a contributing factor; reducing agricultural azole use could help mitigate this issue in human infections.
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Article Synopsis
  • Out of 123 isolates from fruit surfaces, the most common species was identified alongside two others, all showing resistance to fluconazole and non-susceptibility to voriconazole.
  • These resistant strains were linked to the same prevalent genetic type associated with candidemia in patients in Taiwan.
  • The study emphasizes the importance of washing fruit to remove harmful microbes and suggests that reducing fungicide use in agriculture can help preserve effective treatment options for patients.
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Dietary therapies are recommended for the treatment of pediatrics with functional abdominal pain disorders (FAPDs), but the comparative effectiveness among them is unclear. Therefore, the main aim of this systematic review and meta-analysis was to compare the effectiveness of differential dietary therapies in pediatrics with functional abdominal pain disorders. We searched PubMed, Embase, and the Cochrane Central Register of Controlled Trials databases from inception to February 28, 2023.

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To monitor trends in the distribution of yeast species and the susceptibilities of these species to commonly prescribed antifungal drugs, we conduct the Taiwan Surveillance of Antimicrobial Resistance of Yeasts (TSARY) every 4 years. We found that 25 of 294 Candida tropicalis isolates from TSARY 2014 and 31 of 314 C. tropicalis isolates from TSARY 2018 were resistant to fluconazole.

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Most yeasts causing infections in humans are part of commensal microflora and etiological agents of different infections when hosts become susceptible, usually due to becoming immunocompromised. The colonization of potentially pathogenic microbes in the oral cavity is increased by poor oral hygiene. This follow-up survey was conducted approximately two months after providing information on proper oral care at 10 nursing homes in Taiwan.

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Nuclear factor I/B (NFIB) is a widely studied transcription factor that participates in tumor progression; nevertheless, studies on NFIB in colorectal cancer (CRC) are limited. In our study, Western blot and RT-PCR analyses showed that NFIB was overexpressed in CRC tissues and cell lines, which was consistent with our bioinformatic analysis results. Furthermore, NFIB expression was closely related to the TNM stage of CRC.

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Clinically significant yeast isolates were collected via Taiwan Surveillance of Antimicrobial Resistance of Yeasts (TSARY) in 2014, and mixed infections were investigated. Among 44 out of 1092 specimens containing multiple species, 17, 11, 5, 3, and 8 were from urine, sputum, blood, ascites, and 6 others, respectively. There predominant combinations of mixed infection were 14 Candida albicans/Candida glabrata, 13 C.

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Objective: We investigated the diversity and drug susceptibility of pathogenic yeasts on fruit surfaces.

Method: Fruits were purchased from supermarkets and washed with buffer. The pellets were re-suspended in medium after centrifugation.

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The species distribution and drug susceptibilities of 1106 Candida isolates collected in Taiwan Surveillance of Antimicrobial Resistance of Yeasts (TSARY) in 2014 were determined. Candida albicans is still the dominant species, accounting for 35.9%, followed by 28.

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There is distinctive advantage of using male sterile lines to breed new cultivar and produce hybrids, when compared with general breeding method on yield and quality. In our previous work, near-isogenic lines (NILs) of male sterile and fertile Salvia miltiorrhiza have been obtained through continuous hybridization in many years. In this investigation, 378 primer combination were screened by using AFLP and BSA technique, in which 26 markers amplified from seven primers were found to tightly link to male sterile gene.

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