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Publications by authors named "Zi-Heng Wu"

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Synopsis of recent research by authors named "Zi-Heng Wu"

  • - Zi-Heng Wu's recent research primarily focuses on the mechanisms underlying vascular smooth muscle cell (VSMC) behavior in diabetic conditions, highlighting the roles of various molecular pathways and regulatory elements such as dynamin-related protein 1 (DRP1), lncRNA CDKN2B-AS1, and mitophagy in influencing diabetic vascular complications.
  • - Key findings include the therapeutic potential of isoliquiritigenin in combating diabetic intimal hyperplasia by targeting mitochondrial fission through DRP1, and the ability of GLP-1 receptor agonists to mitigate diabetes-related vascular calcification via AMPK signaling pathways.
  • - Additionally, Wu's studies emphasize the involvement of epigenetic mechanisms, including mA methylation modifications and the functions of circular RNAs and long non-coding RNAs in regulating endothelial and VSMC dysfunctions associated with hyperglycemia and diabetes.

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