Publications by authors named "Zi-Chen Yang"
Glutamine metabolism is pivotal in cancer biology, profoundly influencing tumor growth, proliferation, and resistance to therapies. Cancer cells often exhibit an elevated dependence on glutamine for essential functions such as energy production, biosynthesis of macromolecules, and maintenance of redox balance. Moreover, altered glutamine metabolism can contribute to the formation of an immune-suppressive tumor microenvironment characterized by reduced immune cell infiltration and activity.
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- This study examines the effectiveness of whole-body dynamic F-FDG PET/CT imaging in detecting recurrent tumors in patients who have undergone gastric or esophageal cancer surgery, addressing limitations of traditional imaging methods in early detection.
- The research focuses on differentiating between anastomotic recurrence and inflammation in 53 postoperative patients, analyzing abnormal FDG uptake and utilizing advanced software for metabolic and distribution parameters.
- The aim is to improve early diagnosis rates of recurrent tumors, ultimately aiding clinical decision-making for treatment options in high-risk patients.
Article Synopsis
- * UV222 and UV254 show similar effectiveness in inactivating E. coli, but UV222 treatment prevents reactivation by causing extensive damage to the bacteria's DNA and cell membrane.
- * Overall, using UV222 for disinfection may be a better option for water treatment as it minimizes the chance of bacterial recovery after treatment.
Ozone, hydrogen peroxide, and peroxymonosulfate disinfection of MS2 coliphage in water.
Environ Sci Process Impacts
May 2024
Article Synopsis
- - The study investigates how well different oxidants—ozone (O), peroxymonosulfate (PMS), and hydrogen peroxide (HO)—can inactivate the MS2 coliphage virus in water, which is important for preventing viral disease spread.
- - Results showed that to achieve a significant 4-log reduction in virus levels, all three oxidants needed specific doses and a contact time of 30 minutes, but ozone was the fastest, requiring only 0.5 minutes.
- - In secondary effluent, all three oxidants effectively inactivated the virus and removed dissolved organic matter, but ozone was found to be the most efficient option overall for disinfection.
Excessive consumption of sodium salt is one of the important inducers of cardiovascular and cerebrovascular diseases. The reduction of physical labor and attention to health make research on low-sodium salt imminent. Ultrafiltration, gel filtration, preparative high-performance liquid chromatography, and liquid chromatography with tandem mass spectrometry were employed for further purification and identification of the salty enhancing peptides in yeast extracts.
View Article and Find Full Text PDFBackground: In the early stage of severe burn, patients often exhibit a high level of inflammatory mediators in blood and are likely to develop sepsis. High-volume haemofiltration (HVHF) can eliminate these inflammatory mediators. We hypothesised that early application of HVHF may be beneficial in reducing sepsis and improving the prognosis of patients with severe burns.
View Article and Find Full Text PDFThe DEAD-box family of RNA helicase is known to be required in virtually all cellular processes involving RNA, and p68 is a prototypic one of the family. Reports have indicated that in addition to ATPase and RNA helicase ability, p68 can also function as a co-activator for transcription factors such as estrogen receptor alpha, tumor suppressor p53 and beta-catenin. More than that, post-translational modification of p68 including phosphorylation, acetylation, sumoylation, and ubiquitylation can regulate the coactivation effect.
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