Publications by authors named "Zi-Chen Liu"
Article Synopsis
- Hypertension is a growing concern in China, with low control rates among patients, prompting a study on new treatment options.
- A randomized trial compared the effectiveness and safety of sacubitril/allisartan vs. olmesartan in patients with mild-to-moderate hypertension over a 12-week period.
- Results showed that sacubitril/allisartan significantly reduced blood pressure more than olmesartan, and it was well tolerated among participants, with no reports of serious side effects.
Introduction: In August 2021, an outbreak of Feline Panleukopenia Virus (FPV) was observed in four 3-month-old Pallas' cats at Xining Wildlife Park. Despite timely intervention, the Pallas'cat cubs continued to experience clinical symptoms including diarrhea, seizures, and decreased white blood cell count, and all four cats died.
Methods: FPV clinical suspicions were initially confirmed by positive Polymerase Chain Reaction (PCR) testing.
Article Synopsis
- The study investigates the effectiveness of cell-free Mycobacterium tuberculosis DNA (cf-TB) testing as a biomarker for diagnosing tuberculous pleurisy (TP) due to challenges with low bacterial levels in pleural effusion samples.
- Conducted across 11 research sites in China, the study analyzed PE samples from 1344 patients suspected of TP, using techniques like Xpert MTB/RIF and mycobacterial culture alongside cf-TB testing.
- Results revealed that cf-TB testing had a significantly higher sensitivity (73.6%) for definite TP compared to Xpert (40.8%) and mycobacterial culture (54.2%), while maintaining 100% specificity across all tests.
Article Synopsis
- - The study investigates how prior anti-tuberculosis (TB) treatments affect the diagnosis of tuberculous lymphadenitis (TBLN) by evaluating various diagnostic methods like histology, microbiology, and molecular tests.
- - A total of 89 patients were assessed, with significant findings showing that previous TB treatment notably lowered the culture test's effectiveness, while the Xpert test showed reduced sensitivity for those treated for over three months.
- - The researchers concluded that for patients with a history of long-term TB treatment, it is crucial to use a combination of diagnostic tests to minimize the risk of false negatives, especially from the culture method.
The micropapillary (MP) subtype has recently been established to be a distinct marker of poor prognosis in lung adenocarcinomas (LACs). According to the 2015 WHO classification system, LAC constituents are required to be precisely reported. T790M mutation and an insertion in exon 20 (E20ins) are associated with EGFR-TKI resistance.
View Article and Find Full Text PDF