Piezoelectric Energy Harvesting and Body Motion Sensing of a Pair of 0D Chiral Hybrid Metal Halides.

Chiral hybrid metal halides have received considerable attention in circularly polarized luminescence and spintronics due to their structural diversity, ease of synthesis, and chemical versatility. However, only a limited number of chiral metal halides have been utilized in piezoelectric energy harvesters and motion sensors. Furthermore, the exploration of 0D chiral piezoelectric materials is still in their early stage, offering substantial potential for further development.

Structure-guided design and photochemical synthesis of new carbamo(dithioperoxo)thioates with improved potencies to SARS-CoV-2 3CL.

The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has triggered a protracted global pandemic from 2019 to 2022, and posed a significant threat to human health. One of the non-structural proteins 3CL of SARS-CoV-2 is considered as a validated target for the development of inhibitors against the virus. Disulfiram has been reported as a covalent inhibitor of 3CL; however, its structure lacks bonding site with active pockets of 3CL and its highly symmetric structure doesn't match well with the irregular cavity of the active center, limiting its therapeutic applications.

Near-Full-Spectrum Emission Realized in a Single Lead Halide Perovskite across the Visible-Light Region.

The engineering of tunable photoluminescence (PL) in single materials with a full-spectrum emission represents a highly coveted objective but poses a formidable challenge. In this context, the realization of near-full-spectrum PL emission, spanning the visible light range from 424 to 620 nm, in a single-component two-dimensional (2D) hybrid lead halide perovskite, (ETA)PbBr (ETA=(HO)(CH)NH ), is reported, achieved through high-pressure treatment. A pressure-induced phase transition occurs upon compression, transforming the crystal structure from an orthorhombic phase under ambient conditions to a monoclinic structure at high pressure.

Drug release and solubility properties of two zeolitic metal-organic frameworks influenced by their hydrophobicity/hydrophilicity.

Metal-organic frameworks (MOFs) have shown significant potential for drug delivery applications. However, there remains a scarcity of comprehensive research addressing the influence of surface properties of MOFs on drug release kinetics and drug solubility. This study focuses on examining the influence of MOFs hydrophilicity and hydrophobicity on the controlled release and solubility of drugs.

Target-triggered stochastic DNAzyme motors on spherical nucleic acids for simultaneous fluorescence assay of double miRNAs.

Simultaneous quantifications of multiple miRNAs in the single-sampling system would be conducive to the accurate diagnosis of diseases in contrast with single miRNA analysis. In this work, a stochastic DNAzyme motor on spherical nucleic acids (SNAs) for simultaneous fluorescence assay of double miRNAs was established. Hairpin 1 (H1)-FAM-7a and H1-TAMRA-133a-functionalized magnetic beads (MBs) as SNAs were mixed.

Construction of an aflatoxin aptamer sensor based on a DNA nanoprism structure.

Aflatoxin B1 (AFB1) is a group of heterocyclic aromatic hydrocarbon secondary metabolites, which are the most toxic among the known fungal toxins. Therefore, it becomes particularly important to develop sensitive, accurate, rapid and simple methods for the detection of AFB1. In this work, a method of constructing aflatoxin aptasensor with black phosphorus nano sheet loaded with gold nanoparticles as electrode modification material, Ce-metal organic framework (MOF) material as signal label and prism DNA nano structure modified electrode as recognition interface is proposed.

Plastic bending in a semiconducting coordination polymer crystal enabled by delamination.

Coordination polymers (CPs) are a class of crystalline solids that are considered brittle, due to the dominance of directional coordination bonding, which limits their utility in flexible electronics and wearable devices. Hence, engineering plasticity into functional CPs is of great importance. Here, we report plastic bending of a semiconducting CP crystal, Cu-Trz (Trz = 1,2,3-triazolate), that originates from delamination facilitated by the discrete bonding interactions along different crystallographic directions in the lattice.

An electrochemical aptasensor based on intelligent walking DNA nanomachine with cascade signal amplification powered by nuclease for Mucin 1 assay.

Intelligently walking DNA nanomachines have sprung up an upsurge in various nucleic acid testing, but the rapid and sensitive test methods toward disease biomarker proteins based on the signal amplification strategy of DNA nanomachines were still ongoing development. In this work, an electrochemical aptasensor coupling the magnetic separation technique with the nuclease-powered walking DNA nanomachine was established for Mucin 1 (MUC1) detection. The magnetic beads (MBs) were modified by MUC1 aptamer hybridized with blocker DNA probe (BDP).

A visual peroxidase mimicking aptasensor based on Pt nanoparticles-loaded on iron metal organic gel for fumonisin B analysis in corn meal.

A visual colorimetric aptasensor combining platinum nanoparticles (Pt NPs) loaded on Fe-based metal organic gel (Fe-MOG) as peroxidase mimics with magnetic separation technique was designed for the detection of fumonisin B (FB). Interestingly, based on the inherent properties of Fe-MOG such as porous nanostructures, abundant Fe/Fe active metal centers and synergetic effect between Pt NPs and Fe-MOG, Pt NPs/Fe-MOG composites can be employed as excellent peroxidase mimetic enzyme to oxidize 3,3',5,5'-tetramethylbenzidine (TMB) in the presence of HO. This process was accompanied by a color variation of the solution from colorless to blue.

Student-Teacher Relationship: Its Measurement and Effect on Students' Trait, Performance, and Wellbeing in Private College.

Student-teacher relationships (STRs) have been examined by many studies. However, an omission still exists, the existing scales are not appropriate for studying STRs in private colleges because of the special character of these schools. This paper presents the development and validation of Private-College Student-Teacher Relationship Scale (PCSTRS), the first instrument to evaluate student-teacher relationships (STRs) in private colleges.

Temperature-Responsive Photoluminescence and Elastic Properties of 1D Lead Halide Perovskites - and -(Methylbenzylamine)PbBr.

Low-dimensional metal halide perovskites (MHPs) have received much attention due to their striking semiconducting properties tunable at a molecular level, which hold great potential in the development of next-generation optoelectronic devices. However, the insufficient understanding of their stimulus-responsiveness and elastic properties hinders future practical applications. Here, the thermally responsive emissions and elastic properties of one-dimensional lead halide perovskites - and -MBAPbBr (MBA = methylbenzylamine) were systematically investigated via temperature-dependent photoluminescence (PL) experiments and first-principles calculations.

Effects of microplastics pollution on plankton: A review.

Microplastics, a new class of environmental pollutants, accumulates in the environment at an uncontrollable rate, which threatens aquatic organisms. Plankton are the basis of food webs and play a significant role in the material circulation and energy flow of aquatic ecosystems. Plankton are sensitive to various environmental pollutants.

Miliary pattern pulmonary infiltrates in a diabetic patient: Coccidioidomycosis.

This is a case of miliary coccidioidomycosis. This case illustrates the importance of early suspicion for coccidioidomycosis in patients from an endemic area. Early identification and recognition of the disease are important to attain early therapy and disease control.

Association of pet-keeping in home with self-reported asthma and asthma-related symptoms in 11611 school children from China.

Objective: We conducted a cross-sectional study to investigate the associations between domestic pets and respiratory health in children.

Methods: We randomly recruited 11,611 school children from Zhongshan, a southern city in China. Information about the respiratory symptoms and disease history of the recruited children, the status of domestic pets, and other related risk factors were collected from March to July 2016.

Double anti-PL-7 and anti-MDA-5 positive Amyopathic Dermatomyositis with rapidly progressive interstitial lung disease in a Hispanic patient.

Background: Each myositis-specific autoantibody (MSA) tends to have a distinct clinical presentation. Coexistence of MSAs do not commonly occur. If they do, it is unknown if there is an overlap of clinical features or prognostic implications.

Controlled Hierarchical Self-Assembly of Catenated Cages.

Constructing hierarchical superstructures to achieve comparable complexity and functions to proteins with four-level hierarchy is challenging, which relies on the elaboration of novel building blocks with complex structures. We present a series of catenated cages with unique structural complexity and tailorability. The rational design was realized as such: A catenane of two symmetric cages (CSC), , with all rigid imine panels was converted to a catenane of two dissymmetric cages (CDC), , with two exterior flexible amine panels, and was tailored from by introducing an additional methyl group on each blade to increase lateral hindrance.

Amphiphilic Organic Cages: Self-Assembly into Nanotubes and Enhanced Anion-π Interactions.

An amphiphilic organic cage was synthesized and used as self-assembly synthon for the fabrication of novel functional supramolecular structures in solution. The transmission electron microscopy (TEM) results showed that this amphiphilic cage self-assembled in aqueous solution into unilamellar nanotubes with a diameter of 29±4 nm at a concentration of 0.05 mg mL .

De Novo Construction of Catenanes with Dissymmetric Cages by Space-Discriminative Post-Assembly Modification.

Considerable efforts have been made to increase the topological complexity of mechanically interlocked molecules over the years. Three-dimensional catenated structures composed of two or several (usually symmetrical) cages are one representative example. However, owing to the lack of an efficient universal synthetic strategy, interlocked structures made up of dissymmetric cages are relatively rare.

Multicentric Castleman disease with TAFRO syndrome and Sjögren's.

We describe a patient with Castleman's disease with TAFRO syndrome and concurrent Sjögren's syndrome and investigate whether the autoimmune process may have accelerated the onset of her Castleman's disease. Patient was treated with R-CVP therapy with remission of symptoms although there is no current standard treatment.

Heavy Cannabis Use Associated with Wernicke's Encephalopathy.

Cannabis use accounts for more than 149,000 hospital visits annually. As more states legalize recreational Cannabis, side effects that are currently rare or unknown will become increasingly more common. Here, we present one such rare case of Cannabis-induced hyperemesis causing Wernicke's encephalopathy.

The effect of cane length and step height on muscle strength and body balance of elderly people in a stairway environment.

Background: It has been reported that 75% of stairway accidents occur while descending stairs. Using a cane can help to prevent older people and those with limited mobility from falling. However, studies have shown that two-thirds of older cane users use a cane that is longer than the recommended length, which may cause unnecessary muscular loads.