Publications by authors named "Zi Yang Chua"

Background: Medication discrepancies commonly occur when patients are transferred between care settings. Despite the presence of medication reconciliation services (MRS), medication discrepancies are still prevalent, which has clinical costs and implications. This study aimed to explore the perspectives of various stakeholders on how the MRS can be optimized in Singapore.

View Article and Find Full Text PDF
Article Synopsis
  • Asians experience a higher rate of receiving variants of uncertain significance (VUS) results from genetic panel testing, leading to increased anxiety for cancer patients.* -
  • An exploratory study conducted interviews with 20 Asian cancer patients who received VUS results, revealing five key themes around their experiences and coping mechanisms.* -
  • The study emphasizes the need for better genetic counseling practices in Asia to accurately interpret VUS results and improve communication, ultimately reducing anxiety and misinformation in cancer care.*
View Article and Find Full Text PDF

Background: Although Singapore is one of the highest vaccinated countries in the world, vaccine hesitancy remains in a subpopulation, including individuals with cancer predisposition syndromes. At the Cancer Genetics Service National Cancer Centre Singapore, we see patients with germline genetic alterations, most being BRCA1/2 pathogenic/likely pathogenic variant (PV/LPV) carriers. While reported safe for cancer patients, there are limited studies addressing the safety profile and outcomes of COVID-19 vaccination among individuals with germline PV/LPV in cancer predisposition genes such as BRCA1/2.

View Article and Find Full Text PDF

Background: Delineating the compound psychological effect of the pandemic on cancer care, and the interdependency across cancer patient-caregiver dyads have yet to be explored. This study examines the levels of psychological impact of COVID-19 on patient-caregiver dyads anxiety, and the interdependent associations between their COVID-19 and cancer concerns, and risk perceptions.

Method: There were 352 patients and caregivers (patient-caregiver dyads, N = 176) included in this study (43.

View Article and Find Full Text PDF

Objective: This study aimed at determining the feasibility of conducting a large-scale pragmatic effectiveness study on the implementation of multidisciplinary care (MDC) program for patients with advanced chronic kidney disease (CKD).

Methods: This is a single-arm pre-post intervention design pilot study over 12 months. Participants with an estimated glomerular filtration rate (eGFR) between 11 and 20 ml/min/1.

View Article and Find Full Text PDF

Objectives: Having to access life-sustaining treatment during the emerging COVID-19 outbreak has placed patients with cancer at an especially vulnerable position notwithstanding their immunocompromised condition. The present study aimed to elucidate cancer patients' and their caregivers' experiences during this outbreak.

Design: Face-to-face semistructured interviews were conducted.

View Article and Find Full Text PDF

Purpose: The coronavirus disease 2019 (COVID-19) pandemic has had a global impact, and Singapore has seen 33,000 confirmed cases. Patients with cancer, their caregivers, and health care workers (HCWs) need to balance the challenges associated with COVID-19 while ensuring that cancer care is not compromised. This study aimed to evaluate the psychological effect of COVID-19 on these groups and the prevalence of burnout among HCWs.

View Article and Find Full Text PDF