Modified Cuff Leak Test for Predicting the Risk of Reintubation in Patients With Invasive Mechanical Ventilation: A Multicenter, Single-Blind, Randomized Controlled Trial.

Background: The cuff leak test (CLT) is an important tool to assess the risk of upper airway obstruction after extubation.

Research Question: Does a modified CLT approach have superior ability in predicting reintubation compared with the traditional method?

Study Design And Methods: This was a prospective, multicenter, randomized control trial. The primary end point was the incidence of the need for reintubation within 48 hours of extubation.

Characteristic and Import Mechanism of Protein Nuclear Translocation.

Coordination and information exchange among the various organelles ensure the precise and orderly functioning of eukaryotic cells. Interaction between the cytoplasm and nucleoplasm is crucial for many physiological processes. Macromolecular protein transport into the nucleus requires assistance from the nuclear transport system.

Prospective Study of Low- and Standard-dose Chest CT for Pulmonary Nodule Detection: A Comparison of Image Quality, Size Measurements and Radiation Exposure.

Objective: To comprehensively and accurately analyze the out-performance of low-dose chest CT (LDCT) vs. standard-dose CT (SDCT).

Methods: The image quality, size measurements and radiation exposure for LDCT and SDCT protocols were evaluated.

Zwitterionic Manganese and Gadolinium Metal-Organic Frameworks as Efficient Contrast Agents for in Vivo Magnetic Resonance Imaging.

Two water-stable three-dimensional Mn- and Gd-based metal-organic frameworks (MOFs), {[Mn(Cmdcp)(HO)]·HO} (1) and {[Gd(Cmdcp)(HO)](NO)·3HO} (2, HCmdcpBr = N-(4-carboxy benzyl)-(3,5-dicarboxyl)pyridinium bromide), have been prepared and analyzed. In vitro magnetic resonance imaging indicated that MOFs 1 and 2 possess relaxivity r values of 17.50 and 13.