Detection and clinical significance of DNA repair gene ERCC8 tag SNPs in gastric cancer.

Background/aims: Excision repair cross-complementing group 8 (ERCC8) is one of the members of the nucleotide excision repair pathway. This study aimed to explore the association between ERCC8 tag single nucleotide polymorphisms (SNPs) and gastric cancer.

Materials And Methods: Totally, 120 patients with gastric cancer treated from March 2010 to March 2011 were selected as the observation group and 120 healthy individuals were selected as the control group during the same period.

Melatonin Induces Osteoblastic Differentiation of Mesenchymal Stem Cells and Promotes Fracture Healing in a Rat Model of Femoral Fracture via Neuropeptide Y/Neuropeptide Y Receptor Y1 Signaling.

The function of melatonin (MLT) in promoting fracture healing has been demonstrated in previous studies. However, the molecular mechanism underlying therapeutic effects of MLT is not entirely clear. In this study, mesenchymal stem cells (MSCs) were isolated from rat bone marrow and identified by flow cytometry.

Triboelectric microplasma powered by mechanical stimuli.

Triboelectric nanogenerators (TENGs) naturally have the capability of high voltage output to breakdown gas easily. Here we present a concept of triboelectric microplasma by integrating TENGs with the plasma source so that atmospheric-pressure plasma can be powered only by mechanical stimuli. Four classical atmospheric-pressure microplasma sources are successfully demonstrated, including dielectric barrier discharge (DBD), atmospheric-pressure non-equilibrium plasma jets (APNP-J), corona discharge, and microspark discharge.

trans-Hydroboration vs. 1,2-reduction: divergent reactivity of ynones and ynoates in Lewis-base-catalyzed reactions with pinacolborane.

Ynones and ynoates react with pinacolborane in a divergent manner in the presence of nucleophilic phosphine catalysts. Ynones are transformed to the corresponding propargyl alcohols in good yields with high regio- and chemoselectivity. Ynoates undergo highly regio- and stereoselective trans-hydroboration to produce E-vinylboronates.

Effects of ginsenoside Rb1 on oxidative stress injury in rat spinal cords by regulating the eNOS/Nrf2/HO-1 signaling pathway.

The present study aimed to investigate whether ginsenoside Rb1 (G-Rb1) attenuates spinal cord injury-associated oxidative stress in rats by regulating the endothelial nitric oxide synthase eNOS/nuclear factor erythroid 2-related factor 2 (Nrf2)/heme oxygenase (HO)-1 signaling pathway. Sprague Dawley rats were randomly divided into the sham operation group (S group), spinal cord injury group (SCI group), G-Rb1 treatment group (G-Rb1 group) and SCI+G-Rb1+Inhibitor L-name group (L-name group). The posterior limb function was evaluated via the Basso, Beattie and Bresnahan scoring method.

Raising the Working Temperature of a Triboelectric Nanogenerator by Quenching Down Electron Thermionic Emission in Contact-Electrification.

As previously demonstrated, contact-electrification (CE) is strongly dependent on temperature, however the highest temperature in which a triboelectric nanogenerator (TENG) can still function is unknown. Here, by designing and preparing a rotating free-standing mode Ti/SiO TENG, the relationship between CE and temperature is revealed. It is found that the dominant deterring factor of CE at high temperatures is the electron thermionic emission.

BRCA germline mutations in an unselected nationwide cohort of Chinese patients with ovarian cancer and healthy controls.

Objective: To investigate the BRCA status in Chinese patients with ovarian cancer (OC). Though there were two large prevalence studies in Chinese OC patients, this was the first time to observe it in healthy controls.

Methods: We performed BRCA mutation screening using next-generation sequencing to determine the prevalence of BRCA germline deleterious mutations in an unselected cohort of Chinese OC patients (n = 1331) versus healthy controls (n = 1763) and describe the types and spectrum of BRCA deleterious variants.

Triboelectric Nanogenerator (TENG) Mass Spectrometry of Falsified Antimalarials.

Rationale: An epidemic of low quality medicines continues to endanger patients worldwide. Detection of such "medicines" requires low cost, ambient ionization sources coupled to fieldable mass spectrometers for optimum sensitivity and specificity. With the use of triboelectric nanogenerators (TENGs), the charge required to produce gas-phase ions for mass analysis can be obtained without the need for high voltage electrical circuitry, simplifying and lowering the cost of next-generation mass spectrometry instruments.

Acupuncture for ophthalmoplegia: Protocol for a systematic review.

Background: Ophthalmoplegia is a disease that affects many people every year and is caused by reasons, such as cavernous sinus lesion, intracranial aneurysm, diabetes, and trauma. Acupuncture has been widely used to treat ophthalmological diseases especially ophthalmoplegia in China. Many clinical trials indicate that acupuncture may promote the recovery of extraocular muscles in ophthalmoplegia patients.

Sparsity-based signal extraction using dual Q-factors for gearbox fault detection.

Early detection of faults developed in gearboxes is of great importance to prevent catastrophic accidents. In this paper, a sparsity-based feature extraction method using the tunable Q-factor wavelet transform with dual Q-factors is proposed for gearbox fault detection. Specifically, the proposed method addresses the problem of simultaneously extracting periodic transients and high-resonance component from noisy data for the gearboxes fault detection purpose.

Author Correction: Grain Yield, Starch Content and Activities of Key Enzymes of Waxy and Non-waxy Wheat (Triticum aestivum L.).

A correction to this article has been published and is linked from the HTML version of this paper. The error has not been fixed in the paper.

Effects of carboxyl and aldehyde groups on the antibacterial activity of oxidized amylose.

Dialdehyde-amyloses, dicarboxyl-amyloses and dialdehyde-carboxyl-amyloses with different oxidation levels were prepared and used to study the effects of aldehyde and carboxyl groups on the antibacterial activity of oxidized amyloses. The results showed that dicarboxyl-amyloses presented antibacterial activity through acidic pH effect produced by carboxyl groups, which was easily reduced or eliminated by adjusting pH. Dialdehyde-amyloses possessed a broad-spectrum antibacterial activity owing to the reactivity of aldehyde groups rather than acidic pH effect.

Concurrent Harvesting of Ambient Energy by Hybrid Nanogenerators for Wearable Self-Powered Systems and Active Remote Sensing.

Harvesting energy available from ambient environment is highly desirable for powering personal electronics and health applications. Due to natural process and human activities, steam can be produced by boilers, human perspiration, and the wind exists ubiquitously. In the outdoor environment, these two phenomena usually exist at the same place, which contain heat and mechanical energies simultaneously.

All-optical microwave oscillator based on semiconductor optical amplifier and stimulated Brillouin scattering.

An all-optical microwave oscillator is proposed and experimentally demonstrated. Based on a pure photonic feedback loop, this system can generate a photonic microwave signal without optical-electrical-optical conversion or any electrical microwave devices. A semiconductor optical amplifier implements the functions of microwave envelope detection and feedback modulation.

Photonic microwave waveforms generation based on two cascaded single-drive Mach-Zehnder modulators.

A new photonic scheme for various waveforms generation has been proposed and demonstrated. In the scheme, two cascaded single-drive LiNbO Mach-Zehnder modulators serve as pulse shaper and the polarization-dependent character of the modulators is fully exploited and utilized. By arranging the polarization states of the incident light, two different spectra are achieved on two orthogonal polarization components respectively.

High-Output Lead-Free Flexible Piezoelectric Generator Using Single-Crystalline GaN Thin Film.

Piezoelectric generators (PEGs) are a promising power source for future self-powered electronics by converting ubiquitous ambient mechanical energy into electricity. However, most of the high-output PEGs are made from lead zirconate titanate, in which the hazardous lead could be a potential risk to both humans and environment, limiting their real applications. III-Nitride (III-N) can be a potential candidate to make stable, safe, and efficient PEGs due to its high chemical stability and piezoelectricity.

Grain Yield, Starch Content and Activities of Key Enzymes of Waxy and Non-waxy Wheat (Triticum aestivum L.).

Waxy wheat has unique end-use properties; however, its production is limited due mainly to its low grain yield compared with non-waxy wheat. In order to increase its grain yield, it is critical to understand the eco-physiological differences in grain filling between the waxy and non-waxy wheat. In this study, two waxy wheat and two non-waxy wheat cultivars were used to investigate the differences in starch-associated enzymes processes, sucrose and starch dynamics, yield components, and the final grain yield.

Lewis-base-catalysed selective reductions of ynones with a mild hydride donor.

Ynones are efficiently reduced with a mild hydride donor in the presence of a catalytic amount of nucleophilic phosphines. The reactions are selective 1,2-reductions that give propargyl alcohols in yields of up to 96%. It is proposed that success in these reactions depends on the activation of ynones by a Lewis base catalyst.

On the Electron-Transfer Mechanism in the Contact-Electrification Effect.

A long debate on the charge identity and the associated mechanisms occurring in contact-electrification (CE) (or triboelectrification) has persisted for many decades, while a conclusive model has not yet been reached for explaining this phenomenon known for more than 2600 years! Here, a new method is reported to quantitatively investigate real-time charge transfer in CE via triboelectric nanogenerator as a function of temperature, which reveals that electron transfer is the dominant process for CE between two inorganic solids. A study on the surface charge density evolution with time at various high temperatures is consistent with the electron thermionic emission theory for triboelectric pairs composed of Ti-SiO and Ti-Al O . Moreover, it is found that a potential barrier exists at the surface that prevents the charges generated by CE from flowing back to the solid where they are escaping from the surface after the contacting.

Antioxidant action and protective and reparative effects of lentinan on oxidative damage in HaCaT cells.

Background: Lentinus edodes is one of the largest edible fungi. Lentinan, extracted from its fruiting body has clinically significant anticancer, antibacterial, antiviral, and anticoagulant effects; however, its preventive effects on skin oxidative damage are unclear.

Aims: We aimed to evaluate the in vitro antioxidation capability of lentinan and its protective and reparative effects on a model of cell oxidative damage.

Preparation, characterization and antibacterial activity of oxidized κ-carrageenan.

The oxidized κ-carrageenans with different oxidation levels were prepared through the hydrogen peroxide and copper sulfate redox system. The oxidation level of oxidized κ-carrageenan was successfully controlled by adjusting the dosage of hydrogen peroxide. The results showed that the microtopography of oxidized κ-carrageenan changed from rough granules to smooth flakes, mainly resulting from the easily melting property of oxidized κ-carrageenan induced by introduced carboxyl and aldehyde groups.

3D Orthogonal Woven Triboelectric Nanogenerator for Effective Biomechanical Energy Harvesting and as Self-Powered Active Motion Sensors.

The development of wearable and large-area energy-harvesting textiles has received intensive attention due to their promising applications in next-generation wearable functional electronics. However, the limited power outputs of conventional textiles have largely hindered their development. Here, in combination with the stainless steel/polyester fiber blended yarn, the polydimethylsiloxane-coated energy-harvesting yarn, and nonconductive binding yarn, a high-power-output textile triboelectric nanogenerator (TENG) with 3D orthogonal woven structure is developed for effective biomechanical energy harvesting and active motion signal tracking.

[ARTICLE WITHDRAWN] Long Noncoding RNA MEG3 Inhibits Cell Proliferation and Metastasis in Chronic Myeloid Leukemia via Targeting miR-184.

THIS ARTICLE WAS WITHDRAWN BY THE PUBLISHER IN 03/2021. We submitted a manuscript entitled "Long Noncoding RNA MEG3 Inhibits Cell Proliferation and Metastasis in Chronic Myeloid Leukemia via Targeting miR-184", which was published in the 26(2) issue of Oncology Research. But now we found some inaccuracies in this manuscript.

Piezo-Phototronic Effect on Selective Electron or Hole Transport through Depletion Region of Vis-NIR Broadband Photodiode.

Silicon underpins nearly all microelectronics today and will continue to do so for some decades to come. However, for silicon photonics, the indirect band gap of silicon and lack of adjustability severely limit its use in applications such as broadband photodiodes. Here, a high-performance p-Si/n-ZnO broadband photodiode working in a wide wavelength range from visible to near-infrared light with high sensitivity, fast response, and good stability is reported.

Simultaneously Enhancing Light Emission and Suppressing Efficiency Droop in GaN Microwire-Based Ultraviolet Light-Emitting Diode by the Piezo-Phototronic Effect.

Achievement of p-n homojuncted GaN enables the birth of III-nitride light emitters. Owing to the wurtzite-structure of GaN, piezoelectric polarization charges present at the interface can effectively control/tune the optoelectric behaviors of local charge-carriers (i.e.