Construction of central and axial chirality Pd(II)/Bim-catalyzed asymmetric dearomative Michael reaction of polycyclic tropones.

A highly enantioselective Pd/Bim-catalyzed dearomative Michael reaction applying polycyclic tropones as non-benzenoid aromatic Michael acceptors and arylboronic acids as aryl pronucleophiles has been developed. The bridged biaryls bearing central and axial chirality, including pentacyclic cyclohepta[]indoles and 6,7-dihydrodibenzo[,][7]annulen-5-ones, are generally generated in good to high yields and excellent enantioselectivities and can be readily transformed into useful derivatives.

An Observational and Cross-Sectional Study of the Prevalence of Breast Lesions and Metabolic Dysfunction-Associated Fatty Liver Disease and their Relationship in China.

Background And Aims: Metabolic dysfunction-associated fatty liver disease (MAFLD) has been proposed to replace the concept of non-alcoholic fatty liver disease (NAFLD). The relationship between MAFLD and breast lesions has not been reported. Therefore, we aimed to explore their prevalence and relationship among general population.

Relationship between the Metabolic Associated Fatty Liver Disease and Endometrial Thickness in Postmenopausal Women: A Cross-sectional Study in China.

To determine the relationship between the endometrial thickness (ET) and metabolic associated fatty liver disease (MAFLD) in the postmenopausal women who have a comprehensive health examination. This was a population-based, retrospective observational study of the prevalence of MAFLD in 8594 postmenopausal women with different ET in the Quality Control Center of Health Examination in Chongqing, China. Binary and multivariable logistic regression analyses were used to obtain odds ratios and 95% confidence intervals for patients of different ET with MAFLD after adjusting for age.

Prevalence of and risk factors for metabolic associated fatty liver disease in an urban population in China: a cross-sectional comparative study.

Background: Metabolic associated fatty liver disease (MAFLD) is a new definition for liver disease associated with known metabolic dysfunction. Based on new diagnostic criteria, we aimed to investigate its prevalence and risk factors in Chinese population.

Methods: We conducted this study in a health examination population who underwent abdominal ultrasonography in China.

High activity of NiCoO promoted Pt on three-dimensional graphene-like carbon for glycerol electrooxidation in an alkaline medium.

Spinel oxide NiCoO supported on a three-dimensional hierarchically porous graphene-like carbon (3D HPG) material has been firstly used to enhance the activity of Pt for glycerol electrooxidation. The addition of NiCoO into the Pt/HPG catalyst can significantly improve the catalytic performance for glycerol oxidation. When NiCoO is added to the Pt/HPG catalyst, the onset potential is 25 mV more negative than that on the Pt/HPG catalyst without NiCoO.

Irinotecan plus cisplatin compared with etoposide plus cisplatin in patients with previously untreated extensive-stage small cell lung cancer: A meta-analysis.

Objective: To systematically review the effect and safety of irinotecan plus cisplatin (IP) compared with etoposide plus cisplatin (EP) in patients with previously untreated extensive-stage small cell lung cancer (E-SCLC).

Materials And Methods: Databases including PubMed, The Cochrane Library, EMBASE, China National Knowledge Infrastructure, VIP, and WanFang Data were searched for the randomized controlled trials (RCTs) about IP compared with EP in patients with previously untreated E-SCLC from the establishment to June 2016. Two reviewers independently screened literature, extracted data and assessed the methodological quality of included studies.

Transcriptome analysis revealed pivotal transporters involved in the reduction of cadmium accumulation in pak choi (Brassica chinensis L.) by exogenous hydrogen-rich water.

Hydrogen-rich water (HRW) has been widely used in research on plant resistance to Cd. However, the underlying molecular mechanism of HRW in ameliorating cadmium stress in vegetables is largely unknown. In this study, the RNA-sequencing analyses were used to characterize the role of HRW in the alleviation of Cd toxicity in Chinese cabbage seedlings.

Low molecular weight heparin in treating patients with lung cancer received chemotherapy: A meta-analysis.

Objective: To systematically review the efficacy and safety of low molecular weight heparin (LMWH) in treating patients with lung cancer received chemotherapy.

Materials And Methods: Databases including PubMed, The Cochrane Library, Excerpt Medica Database, Chinese Biomedical Literature Database, China National Knowledge Infrastructure, VIP, and Wanfang Data were searched for the randomized controlled trials (RCTs) about LMWH in treating patients with lung cancer received chemotherapy from the establishment to May 31, 2015. According to the inclusion and exclusion criteria, two reviewers independently screened literature, extracted data, and assessed quality of the included studies.

[Erythropoietin accelerates the proliferation of glioma cells via activating Akt pathway].

Objective: To determine whether erythropoietin (EPO) promotes rapid proliferation of glioma through Akt pathway.

Methods: We detected the expression of EPO in human glioma tissues using immunohistochemistry. A nude mouse model bearing human glioma U87 cell xenograft was established and given intraperitoneal injection of EPO or saline every other day, and the tumor growth was observed.

Status of lipid and lipoprotein in female breast cancer patients at initial diagnosis and during chemotherapy.

Background: The lipid profile status among breast cancer patients at initial diagnosis and during chemotherapy remain controversial. The aim of this study is to study the status of lipid and lipoprotein in female breast cancer patients at initial diagnosis and during chemotherapy.

Methods: We conducted a retrospective cohort study of the status of the lipid and lipoprotein in 1054 primarily diagnosed breast cancer patients and 2483 normal controls with age stratification, from July 2015 to October 2016.

Hepatitis B virus reactivation and antiviral prophylaxis during lung cancer chemotherapy: A systematic review and meta-analysis.

Background: Antiviral drugs have been recommended as prophylaxis for the reactivation of hepatitis B virus (HBV) infection in cancer patients undergoing chemotherapy. However, screening and antiviral prophylaxis for lung cancer remain controversial because of insufficient evidence.

Purpose: In this study, we investigate the absolute risk for HBV reactivation and the prophylactic effects of antiviral drugs in hepatitis B surface antigen (HBsAg)-positive lung cancer patients during chemotherapy.

HIST1H3D: A promising therapeutic target for lung cancer.

HIST1H3D gene encodes histone H3.1 and is involved in gene-silencing and heterochromatin formation. HIST1H3D expression is upregulated in primary gastric cancer tissue.

E-cadherin gene methylation in lung cancer.

E-cadherin, a tumor repressor gene, has been shown to play an important role in maintaining the polarity and structural integrity of epithelial and is closely associated with tumorigenesis, invasion, and metastasis. The current study aimed to investigate the effects of E-cadherin methylation on lung cancer (LC) quantitatively through a meta-analysis. We searched electronic databases to identify eligible studies from their inception through September 30, 2013.

Prognosis value of HIF-1α expression in patients with non-small cell lung cancer.

Background: Hypoxia-inducible factor 1 (HIF-1) is a transcription factor that plays a critical role in the development and progression of tumors. Various studies evaluating the prognostic value of HIF-1α in patients with lung cancer (LC) remain controversial. To comprehensively and quantitatively summarize the evidence on the effect of HIF-1α expression on the survival of patients with LC, a meta-analysis was carried out.

Seroprevalence and risk factors of Chlamydia infection in dogs in Southwestern China.

Chlamydia spp. are obligate intracellular bacteria distributed globally, known to cause various forms of diseases in animals and humans. To date, there is limited information about the seroprevalence of Chlamydia and the risk factors associated with Chlamydia infection in dogs in the world.

[Effects of acupuncture at "Zusanli" (ST 36) on eosinophil apoptosis and related gene expression in rats with asthma].

Objective: To observed efficacy differences of acupuncture at "Zusanli" (ST 36) in rats with asthma and asthma with spleen-deficency, so as to investigate the therapeutic mechanism.

Methods: Sixty SD rats were randomly divided into 5 groups according to their weight, named as an asthma with spleen-deficency group (group A), an acupuncture on asthma with spleen-deficency group (group B), an asthma group (group C), an acupuncture on asthma group (group D) and a control group. The rat models with spleen-deficiency in the first two groups were set up by TCM, then the rats of asthma model in the first four groups were induced by egg albumin, but the control group was treated by the same dose of saline.

Seroprevalence of Toxoplasma gondii infection in pet dogs in Kunming, Southwest China.

Background: Toxoplasmosis is a zoonotic parasitic disease caused by the protozoan Toxoplasma gondii, which infects almost all warm-blooded animals, including humans, with a worldwide distribution. However, little is known of T. gondii seroprevalence in pet dogs in Kunming, the capital of Yunnan Province, southwest China.

[DRIFTS study of Cu1Zr1Ce9Odelta catalysts for selective CO oxidation].

The Cu1Zr1Ce9Odelta catalysts synthesized with coprecipitation method were used into the selective CO oxidation in hydrogen-rich gas. The adsorbed species and the intermediates on Cu1Zr1Ce9Odelta catalysts were examined by in-situ diffuse reflectance FTIR spectroscopy (in-situ DRIFTS) technique. It was found that hydrogen, oxygen and CO in the feed stream were adsorbed competitively at the same adsorption sites on the surface of Cu1Zr1Ce9Odelta catalysts.

[Study on CuO-CeO2 catalysts doped with alkali and alkaline earth metal oxides by in-situ DRIFTS].

CuO-CeO2 series catalysts are the effective catalysts for the selective CO oxidation in hydrogen-rich gas. The adsorption species on the CuO-CeO2 catalysts doped with alkali and alkaline earth metal oxides were investigated with in situ diffuse reflectance FTIR spectroscopy (in-situ DRIFTS) technique. The results showed that a bane at 2 106 cm(-1), due to the carbonyl species, appeared on the CuO-CeO2 catalysts.

[UV-Vis, FTIR and XRD spectroscopic analysis for the preparation of Pt/CNTs electrocatalysts].

Carbon nanotubes (CNTs) supported platinum electrocatalyst Pt/CNTs with high dispersion were prepared by a modified ethylene glycol method with sodium dodecyl sulfate (SDS) as the stabilizer. UV-Vis, FTIR and XRD spectroscopic analysis methods were used to study the preparation of the electrocatalysts, and the effect of the SDS addition to the ethylene glycol solution on the structure as well as the electrocatalytic activity of the Pt/CNTs electrocatalysts were also investigated. The results showed that PtCl6(2-) could form a complex compound with SDS, and all PtCl6(2-) were completely reduced by ethylene glycol; oxygen containing groups were produced on the surface of CNTs to facilitate the Pt nanoparticle absorption, and no SDS remained on the electrocatalysts; the Pt/CNTs electrocatalysts exhibited face-centered cubic structure; the particle size of Pt/CNTs-2 catalyst prepared by SDS addition was about 4.

[Preparation of premonitory Li(x)MoS2 and its spectral analysis].

Under the effect of ultrasonic waves, premonitory Li(x)MoS2 was prepared by n-butyl lithium intercalating in the MoS2 layers, using the single-molecular-layer exfoliated-restacked technology. The value of x was in the range from 0.93 to 0.