Publications by authors named "Zi Jian Dong"
Article Synopsis
- - The infection leads to cyst formation in host muscle cells, allowing the pathogen to avoid the immune response and grow, but the specific factors and mechanisms behind this are not well understood.
- - Researchers discovered that a protein called -RNF, secreted by the pathogen, is essential for its growth and development inside host cells.
- - The -RNF protein acts as an E3 ubiquitin ligase, modifying the SQSTM1/p62 protein in a way that disrupts the normal process of autophagy, which is critical for clearing damaged mitochondria and supports abnormal muscle cell development.
