Adjusting the Structure-Activity Relationship of MOFs to Obtain Electrocatalysts with Higher Hydrogen Evolution and Urea Oxidation Performance by Introducing Different Linkers.

Three kinds of metal-organic frameworks possessing analogous structures were prepared by regulating the structure units of organic linkers. MOF/nickel foam electrocatalysts were formed by in situ hydrothermal growth of MOFs on a clean supported substrate nickel foam (NF), and the corresponding composites were prepared. We phosphatated them and obtained the heterojunction catalyst.

Topological Phase Transitions in Disordered Electric Quadrupole Insulators.

We investigate disorder-driven topological phase transitions in quantized electric quadrupole insulators in two dimensions. We show that chiral symmetry can protect the quantization of the quadrupole moment q_{xy}, such that the higher-order topological invariant is well defined even when disorder has broken all crystalline symmetries. Moreover, nonvanishing q_{xy} and consequent corner modes can be induced from a trivial insulating phase by disorder that preserves chiral symmetry.

Flavopiridol Protects Bone Tissue by Attenuating RANKL Induced Osteoclast Formation.

Bone resorption and homeostasis is carried out by osteoclasts, whose differentiation and activity are regulated by the RANK/RANKL axis. Our previous studies using a mouse model of joint injury show that joint trauma induces local inflammation followed by bone remodeling. The transcription factor cyclin-dependent kinase 9 (CDK9) is the major regulator of inflammation, as CDK9 inhibitor flavopiridol effectively suppress injury-induced inflammatory response.

Vertebral heights and ratios are not only race-specific, but also gender- and region-specific: establishment of reference values for mainland Chinese.

Unlabelled: This study established gender-specific reference values in mainland Chinese (MC) and is important for quantitative morphometry for diagnosis and epidemiological study of osteoporotic vertebral compressive fracture. Comparisons of reference values among different racial populations are then performed to demonstrate the MC-specific characteristic.

Purpose: Osteoporotic vertebral compressive fracture (OVCF) is a common complication of osteoporosis in the elder population.

Coexistence of harmonic soliton molecules and rectangular noise-like pulses in a figure-eight fiber laser.

We report the coexistence of high-order harmonic soliton molecules and rectangular noise-like pulses (NLP) in a figure-eight fiber laser mode-locked by a nonlinear amplifying loop mirror. The harmonic soliton molecule has a repetition rate of 936.6 MHz, corresponding to the 466th harmonics of the fundamental cavity repetition rate, with soliton separation of 16.

Photonic crystal fiber for supporting 26 orbital angular momentum modes.

We propose and numerically investigate a photonic crystal fiber (PCF) based on AsS for supporting the orbital angular momentum (OAM) modes up to 26. The designed PCF is composed of four well-ordered air hole rings in the cladding and an air hole at the center. The OAM modes can be well separated due to the large effective index difference of above 10 between the eigenmodes and maintain single-mode condition radially.

Cyclin-dependent kinase 9 inhibition protects cartilage from the catabolic effects of proinflammatory cytokines.

Objective: Cyclin-dependent kinase 9 (CDK-9) controls the activation of primary inflammatory response genes. The purpose of this study was to determine whether CDK-9 inhibition protects cartilage from the catabolic effects of proinflammatory cytokines.

Methods: Human chondrocytes were challenged with different proinflammatory stimuli (interleukin-1β [IL-1β], lipopolysaccharides, and tumor necrosis factor α) in the presence or absence of either the CDK-9 inhibitor flavopiridol or small interfering RNA (siRNA).