Rhodamine 6G-PAH probes for heavy metal: Fluorescence detection, bioimaging, and solid-phase sensing application.

Four rhodamine 6G-PAH probes with pyrene (R6G-Pyr), anthracene (R6G-Ant), acenaphthene (R6G-Acp) or phenanthrene (R6G-PA) as fluorophore were designed and synthesized for Hg(II) detection. Probe R6G-PA, which had the lowest detection limit of 0.84 nmol/L, displayed the best fluorescence performance as compared to the other three probes.

M-targeted anti-SARS-CoV-2 inhibitor-based drugs.

The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 is a global health emergency. The main protease is an important drug target in coronaviruses. It plays an important role in the processing of viral RNA-translated polyproteins and is highly conserved in the amino acid sequence and three-dimensional structure, making it a good drug target for which several small molecule inhibitors are available.

Preparation of Functionalized Magnetic Polystyrene Microspheres and Their Application in Food Safety Detection.

Based on the specific binding of sulfonic acid groups to melamine, β-agonists and other compounds, FeO nano-magnetic beads were coated with polystyrene using an improved micro-suspension emulsion polymerization method, thus forming core-shell magnetic polystyrene microspheres (FeO@PS) with FeO as the core and polystyrene as the shell. These functionalized microspheres, which can be used as magnetic solid-phase extraction (MSPE) adsorbent, were prepared after further sulfonation. These microspheres were characterized by Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), transmission electron microscopy (TEM), particle size analysis and saturation magnetization measurement.

Preparation of chitosan-coated polystyrene microspheres for the analysis of trace Pb(ii) ions in salt by GF-AAS assisted with solid-phase extraction.

The content of heavy metals is an important index to measure the quality and safety of salt. However, due to the high content of Na(i) in salt causing a large background interference, it is difficult to accurately analyze trace Pb(ii) through the existing atomic absorption spectrometry. Therefore, it is of great significance to design a new solid-phase extraction (SPE) material for the removal and determination of Pb(ii) from salt.