Fungal β-1, 3-glucanosyltransferases: A comprehensive review on classification, catalytic mechanism and functional role.

β-1,3-Glucans form the major carbohydrate component of fungal cell walls, playing a vital role in cell viability, stress response, virulence, and even healthy functions such as immuno-enhancement. The elongation and branching of β-1,3-glucans is a mystery. More evidence proved the β-1, 3-glucantransferases belonging to GH72 or GH17 family to branch and remodel the synthesized linear β-1, 3-glucan chain by cleaving its internal β-1, 3-linkage and transfer the cleaved fragment to the nonreducing end of another β-1, 3-glucan acceptor.

Nonenveloped Avian Reoviruses Released with Small Extracellular Vesicles Are Highly Infectious.

Vesicle-encapsulated nonenveloped viruses are a recently recognized alternate form of nonenveloped viruses that can avoid immune detection and potentially increase systemic transmission. Avian orthoreoviruses (ARVs) are the leading cause of various disease conditions among birds and poultry. However, whether ARVs use cellular vesicle trafficking routes for egress and cell-to-cell transmission is still poorly understood.

Pneumonia caused by Mycobacterium tuberculosis.

Tuberculosis (TB) is one of the top ten leading causes of death worldwide. The causative agent of TB is Mycobacterium tuberculosis. Acute tuberculous pneumonia (TP) is an acute form of pulmonary TB.

Sensitization of avian pathogenic Escherichia coli to amoxicillin in vitro and in vivo in the presence of surfactin.

The purpose of this study is to assess the antibiotics adjuvant effect of surfactin for boosting the treatment effect of amoxicillin. Surfactin is used as a surfactant to mediate flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes. In this study, we demonstrated that surfactin can increase the activity of amoxicillin against avian pathogenic Escherichia coli (APEC) in vitro with antimicrobial assays such as minimum inhibitory concentrations (MIC) and fractional inhibitory concentration (FIC).