PCDHGA10 as a potential prognostic biomarker and correlated with immune infiltration in gastric cancer.

Background: Gastric cancer (GC) is one of the most common malignant tumors and is associated with poor prognosis. To improve the prognosis of GC patients, an effective immune-related prognostic biomarker is urgent. Here, we aim to explore the correlation between the expression of procalcitonin gamma subfamily A, 10 (PCDHGA10) and clinicopathological characteristics, especially its relation with tumor-infiltrating immune cells (TILs) in GC.

Impact of virgin and recycled polymer fibers on the rheological properties of cemented paste backfill.

The addition of polymer fibers to cemented paste backfill (CPB) has shown promise in enhancing mechanical properties, although it also introduces changes in rheological characteristics. This study aimed to investigate the influence of different types of polymer fibers, namely virgin commercial polypropylene fiber (CPPF), recycled tire polymer fiber (RTPF), and recycled tire rubber fiber (RF), on the rheological properties of CPB mixtures through an experimental program, and provide design references for CPB pipeline transport. The results revealed consistent reductions in bulk density upon the incorporation of polymer fibers into CPB, alongside varying impacts on slump.

Experimental study on uniaxial creep characteristics of sandstone with pre-peak unloading damage.

Deep resource extraction has been affected by the complex geological environment of "three highs and one disturbance" for a long time. The surrounding rocks experience strong unloading stress disturbance during the underground resource extraction. The creep characteristics of the perimeter rocks are of great theoretical and practical value.

A Support Vector Machine and Particle Swarm Optimization Based Model for Cemented Tailings Backfill Materials Strength Prediction.

This study aimed to investigate the feasibility of using a model based on particle swarm optimization (PSO) and support vector machine (SVM) to predict the unconfined compressive strength (UCS) of cemented paste backfill (CTB). The dataset was built based on the experimental UCS values. Results revealed that the categorized randomly segmentation was a suitable approach to establish the training set.

Performance Investigation and Cost-Benefit Analysis of Recycled Tire Polymer Fiber-Reinforced Cemented Paste Backfill.

To alleviate the environmental problems caused by scrap tire and tailings disposal, the performance of recycled tire polymer fiber (RTPF)-reinforced cemented paste backfill (CPB) was investigated. Ordinary CPB, commercial poly-propylene fiber (CPPF) and reinforced CPB were also investigated for comparison. Slump tests, unconfined compression tests and a cost-benefit analysis were conducted.

Evaluation of white sandstone mechanical behaviour and the energy evolution of prepeak unloading damage.

Deep high-stress roadway excavation under unloading disturbance inevitably leads to damage deterioration of the surrounding rock, which poses a serious threat to its stability. To explore the energy characteristics of white sandstone damaged by peak front unloading, uniaxial compression tests were conducted on damaged rock samples. The results show that the peak strength and modulus of elasticity of the rock sample gradually decrease with increasing damage degrees.

Mechanical analysis and failure modes prediction of composite rock under uniaxial compression.

Composite rocks are easily encountered in a wide range of geotechnical construction projects. Understanding their mechanical properties and failure modes is very important to ensure project quality and safety. This study conducted a mechanical analysis to assess the stress distribution in composite rock with a horizontal interlayer and predicted the possible failure modes.