Schlafen5, regulated by the AP-1 family transcription factor c-Fos, affects diabetic wound healing through modulating PI3K/Akt/NRF2 axis.

Diabetic ulcers (DUs) present significant physical and psychological challenges to patients, while placing a significant economic burden on healthcare systems. Promoting the blood vessel regeneration is critical for ensuring the delivery of essential nutrients and oxygen to the injured area, thereby supporting the healing process. To gain insight into the complex molecular mechanisms that drive DUs healing, we performed a comprehensive analysis of single-cell transcriptomic data from healing and non-healing DU states.

The effects of fibroblast growth factor-23 on diagnosis of cerebral infarction and vertebral basilar artery stenosis.

Objectives: This study aimed to explore the correlation between Fibroblast Growth Factor-23 (FGF23) levels and Cerebral Infarction (CI), and to determine whether there is a significant relationship between FGF23 and the occurrence and severity of CI.

Methods: The study categorized Cerebral Infarction (CI) patients into severe and mild stenosis groups based on vertebrobasilar artery stenosis, using Digital Subtraction Angiography (DSA) and Magnetic Resonance Imaging (MRI). The study compared the levels of Fibroblast Growth Factor-23 (FGF23) in the serum of CI patients and healthy controls using a t-test and evaluated the diagnostic effectiveness of serum FGF23 using a Receiver Operating Characteristic (ROC) curve.

Well-defined alginate oligosaccharides ameliorate joint pain and inflammation in a mouse model of gouty arthritis.

Gouty arthritis causes severe pain and inflammation. Alginate oligosaccharides (AOSs) are natural products derived from alginate and have anti-inflammatory properties. We explored the potential effects of AOSs with different degrees of polymerization (Dp) on gouty arthritis and associated mechanisms.

Detecting moving targets in active sonar echograph of harbor environment using robust high-order flux tensor.

An important goal of an active sonar system is to detect and track underwater intruders such as frogmen, unmanned underwater vehicles, etc. Unfortunately, the intruders appear visually as a small fluctuating "blob" against the high-level fluctuating background caused by multipath propagation and reverberation in the harbor environment, making it difficult to be distinguished. Classical motion features well developed in computer vision cannot cope with an underwater environment.

Antibiotics affected the bacterial community structure and diversity in pore water and sediments with cultivated in a typical Chinese shallow lake.

The migration of antibiotics and bacterial communities between sediments and pore water occurring in the lake, which is affected by aquatic vegetation. However, the differences in bacterial community structure and biodiversity between pore water and sediments with plants in lakes under antibiotic stress are still poorly understood. We collected pore water and sediments in both wild and cultivated regions in the Zaozhadian (ZZD) Lake to explore the characteristics of the bacterial community.

Motion acoustic flow field: Underwater small target motion characterization for active sonar echograph of harbor environment.

Spatial-temporal variations of active sonar echo intensity can provide effective motion information for characterizing intruding small targets and play a key role in follow-up tracking, behavioral analysis, and recognition, etc. Inspired by the idea of optical flow, which can be used to calculate subtle spatial-temporal variations of each pixel in image sequences, a different motion acoustic flow field (MAFF) is proposed for estimating the motion of underwater small targets in successive active sonar echographs from harbor environments. This is because directly applying current calculation framework for optical flow presents two challenges in this case.

Metagenomics reveals biogeochemical processes carried out by sediment microbial communities in a shallow eutrophic freshwater lake.

Introduction: As the largest shallow freshwater lake in the North China Plain, Baiyangdian lake is essential for maintaining ecosystem functioning in this highly populated region. Sediments are considered to record the impacts of human activities.

Methods: The abundance, diversity and metabolic pathways of microbial communities in sediments were studied by metagenomic approach to reveal patterns and mechanism of C, N, P and S cycling under the threat of lake eutrophication.

Ecological risk assessment of glyphosate and its possible effect on bacterial community in surface sediments of a typical shallow Lake, northern China.

Glyphosate is a widely used herbicide worldwide and its prevalent presence in aquatic ecosystems poses a threat to living organisms. This study evaluated potential ecological risk of glyphosate to sediment-dwelling organisms and assessed the probable effect of glyphosate on structure and predicated function of sediment-attached bacterial communities from a large shallow lake in northern China based on 16S rRNA high-throughput sequencing. Results suggested that glyphosate showed a medium to high concentration (up to 8.

Characterizing bacterial communities in rhizosphere and non-rhizosphere sediments under pressure of antibiotics in a shallow lake.

Introduction: Antibiotics are ubiquitous pollutants and widely found in aquatic ecosystems, which of rhizosphere sediment and rhizosphere bacterial communities had certain correlation. However, the response of bacterial communities in rhizosphere and non-rhizosphere sediments to antibiotics stress is still poorly understood.

Methods: To address this knowledge gap, the samples of rhizosphere (R) and non-rhizosphere (NR) sediments of .

Optimizing spatial interpolation method and sampling number for predicting cadmium distribution in the largest shallow lake of North China.

Cadmium (Cd) pollution has been widely recognized in lake ecosystems. Although the accurate prediction of the spatial distributions of Cd in lakes is important for controlling Cd pollution, the traditional monitoring methods of setting discrete and limited sampling points cannot actually reflect the continuous spatial distribution characteristics of Cd. In this study, we set up 93 sampling points in Baiyangdian Lake (BYDL), and collected surface water, overlying water and sediment samples from each sampling point.

Fate and ecological risks of antibiotics in water-sediment systems with cultivated and wild Phragmites australis in a typical Chinese shallow lake.

River carrying antibiotics from upstream posed serious threats to receiving lake, and plants might had effects on antibiotics. Therefore, samples of waters, sediments and tissues of cultivated and wild Phragmites australis were collected to analyse antibiotics fate and ecological risks (RQs) in Zaozhadian Lake. Our results revealed that the total antibiotics showed an increasing tendency in surface/pore water and P.

Fast online high-order time lacunarity for characterizing active sonar echographs of harbor environment.

High-order time lacunarity (HOT-Lac) is an effective feature for characterizing active sonar echographs of harbor environments. However, it involves high computational complexity of loop summations. Motivated by the idea of integral image, this Letter extends an echo-intensity integral sequence, a representation of filtering with time domain recursion, permitting fast and online updates of HOT-Lac in a constant number of operations.

Effects of flooding frequencies on soil carbon and nitrogen stocks in river marginal wetlands in a ten-year period.

Wetland hydrology can greatly influence the variations in soil carbon and nitrogen stocks. Soil cores were sampled to a depth of 100 cm at 10 cm intervals above 20 cm soils and 20 cm intervals below 20 cm soils in river marginal wetlands with different flooding frequencies (i.e.