The Single Nucleotide Polymorphisms rs4143370 and rs34904192 in MIR155HG Were Associated with Esophageal Cancer Risk in the Chinese Han Population.

Introduction: MIR155HG has been found to play an important role in malignant tumors, but little research has been done on its association with esophageal cancer (ESCC). The aim of this study was to investigate the relationship between MIR155HG polymorphisms and ESCC susceptibility in the Chinese Han population.

Methods: 511 ESCC patients and 487 healthy controls were selected for this study.

CYP3A4 genetic variants are associated with susceptibility of non-small cell lung cancer in a Shaanxi Han population.

Purpose: Lung cancer (LC) is one of the fastest-growing malignant tumors in the world in terms of morbidity and mortality. CYP3A4 plays a crucial role in the occurrence of LC. Little is known about the contribution of CYP3A4 polymorphisms for non-small cell lung cancer (NSCLC) risk.

Effect of IL2RA and IL2RB gene polymorphisms on lung cancer risk.

Background: Inflammation is crucial for lung cancer development. Variants of multiple genes in inflammation pathways may lead to susceptibility to lung cancer. In the present study, we aimed to assess the influence of polymorphisms in inflammation-related genes (IL2RA and IL2RB) on lung cancer risk.

Role of Nampt and Visceral Adiposity in Esophagogastric Junction Adenocarcinoma.

Nampt including eNampt and iNampt may contribute to mediating obesity-associated cancers. This study investigated the role of Nampt in esophagogastric junction adenocarcinoma (EGA), a cancer strongly correlated with obesity. Visceral adiposity was defined by waist circumference or VFA.

Combined thoracoscopic and laparoscopic esophagectomy: experience, technique and cautions.

We described a 59-year-old female, who came to our institute with the diagnosis of esophageal squamous cell carcinoma. The preoperative clinical diagnosis was stage II esophageal squamous cell carcinoma. The three-stage minimally invasive esophagectomy (MIE), combined thoracoscopic-laparoscopic esophagectomy with cervical anastomosis, was performed in this case.

Expression and significance of vascular endothelial growth factor C from multiple specimen sources in esophageal squamous cell carcinoma.

Background: Esophageal squamous cell carcinoma (ESCC) is a common malignancy with a very poor prognosis. Vascular endothelial growth factor C (VEGF-C) plays an important role in angiogenesis and lymphangiogenesis. This study was designed to analyze the correlation of VEGF-C expression with clinicopathological features and survival in multiple specimen sources from patients with ESCC.