Publications by authors named "Zhuoni Li"

Article Synopsis
  • - The study investigates how Eucommiae cortex polysaccharides (EPs) impact gut microbiota and neuroinflammation in mice subjected to chronic unpredictable stress (CUMS), showing EPs can significantly improve gut health and behavioral issues.
  • - After 4 weeks of CUMS, mice treated with EPs exhibited increased beneficial gut bacteria and decreased harmful bacteria, which helped reduce intestinal inflammation and improve neurogenesis in the hippocampus, leading to better behavior.
  • - However, the study does not establish a clear causal link between the changes in gut microbiota due to EPs and the observed behavioral improvements, indicating a need for further research.
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The high fat and sucrose diet, known as the obesogenic diet (OD), has been related to low-grade chronic inflammation and neurodevelopmental disorders. Emerging evidence suggests that OD influences cognitive and social function via the gut-brain axis. However, the effects of OD during adolescence on future health have been unclear.

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