Analyzing the molecular mechanism of xuefuzhuyu decoction in the treatment of pulmonary hypertension with network pharmacology and bioinformatics and verifying molecular docking.

Background: XueFuZhuYu (XFZY), a typical Chinese herbal formula, has remarkable clinical effects for treating Pulmonary Hypertension (PH) with unclear mechanisms. Our research involved the utilization of network pharmacology to explore the traditional Chinese herbal monomers and their related targets within XFZY for PH treatment. Furthermore, molecular docking verification was performed.

Synergizing the enhanced RIME with fuzzy K-nearest neighbor for diagnose of pulmonary hypertension.

Pulmonary hypertension (PH) is an uncommon yet severe condition characterized by sustained elevation of blood pressure in the pulmonary arteries. The delaying treatment can result in disease progression, right ventricular failure, increased risk of complications, and even death. Early recognition and timely treatment are crucial in halting PH progression, improving cardiac function, and reducing complications.