Publications by authors named "Zhuogeng Chen"

Objective: This meta-analysis aims to evaluate the comparative clinical efficacy of photodynamic therapy (PDT) versus other non-surgical treatments in managing peri-implantitis.

Methods: Computer searches were conducted in databases including PubMed, The Cochrane Library, Embase, China National Knowledge Infrastructure (CNKI), VIP, and Wanfang for randomized controlled trials (RCTs) on the clinical efficacy of Photodynamic Therapy (PDT) compared to other non-surgical methods in the treatment of peri-implantitis. The search period spanned from May 2000 to May 2023.

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Objective: To compare the effects of bone grafting versus non-bone grafting on implant stability and new bone formation in patients undergoing maxillary sinus floor lift combined with placement of a Bicon short dental implant.

Methods: We recruited 60 patients with posterior maxillary tooth loss and insufficient jaw bone mass from December 2017 to December 2019, and the patients were divided into 2 groups in accordance with the surgical method: the bone grafted group (n = 32) and the non-bone grafted group (n = 28). Both groups underwent maxillary sinus floor elevation combined with Bicon short dental implant placement.

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Article Synopsis
  • The study aimed to assess the effectiveness of a new artificial bone composed of nano-grade pearl powder, chitosan-hyaluronic acid, and recombinant human bone morphology protein-2 (rhBMP-2) for promoting bone healing.
  • A bone defect was created in the femur of test subjects, with different groups receiving various treatments, including a control group with no material and an experimental group with the new composite.
  • Results showed that after 12 weeks, the experimental group had complete bone repair and significant new bone formation compared to control and blank groups, with no adverse effects, indicating the composite's potential for effective bone repair.
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Objectives: To compare the effect on proliferation of osteoblasts MC3T3-E1 between the concentrated growth factor extract (CGFe) and the platelet-rich fibrin extract (PRFe).

Methods: CGFe and PRFe were prepared. MC3T3-E1 was cultured in DMEM medium containing CGFe (10%, 20%, or 30%) and PRFe (10%, 20%, or 30%).

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Objectives: To evaluate the repairing ability of nano-pearl powder bone substitute in rabbit with defect of distal femur bone.

Methods: Thirty-two New Zealand rabbits were randomly divided into four groups: a nano-pearl powder/recombinant human bone morphogenetic protein 2 (rhBMP-2)/hyaluronic acid group, a nano-pearl powder/hyaluronic acid group, a nano-pearl powder group and a blank control group (=8 in each group). A defect with the diameter of 7 mm and height of 10 mm was prepared at the distal femoral metaphysis line of the rabbit.

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Background: Several studies have examined the association between the IL-13 -1112C/T polymorphism and the risk of periodontitis. However, these studies have reached different conclusions. The aim of the current study was to investigate the link between this IL-13 -1112 polymorphism and susceptibility to periodontitis.

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Purpose: To investigate whether prophylactic antibiotics are beneficial on patients undergoing routine dental implant placement procedures and to investigate which administration regimen is the most effective.

Methods: The primary outcome was implant failure; the secondary outcome was postoperative infection. In the fixed-effects model, the Mantel-Haenszel method was used to calculate pooled relative risks (RRs) at 95% confidence intervals (CIs).

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Objective: The position of the mental foramen and the anterior loop length of the inferior alveolar nerve serve as important anatomical landmarks for surgical procedures in the anterior mandibular region. The purpose of this study was to determine the relationship between the anterior loop of the inferior alveolar nerve and the mental foramen by combining cone beam computed tomography and Mimics, a software used to construct 3-dimensional (3D) interactive models of anatomical structures.

Methods: Cone beam computed tomography images from a total of 60 patients were obtained and studied using GALAXY viewer or were imported into Mimics.

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