Publications by authors named "Zhuoga Deqing"

Article Synopsis
  • Berberine (BBR) is commonly used to treat diarrhea, but its effects on male reproductive health have not been fully understood, prompting this study.
  • After administering BBR to male mice for 14 days, researchers observed significant reductions in testosterone levels, sperm concentration, mating rates, and overall fertility, with testosterone treatment showing partial recovery effects.
  • The study identifies a decrease in a specific gut bacteria called Muribaculaceae as a key factor leading to fertility issues, suggesting that restoring this bacteria through fecal microbiota transplantation or ornithine supplementation may improve testosterone levels and sperm production.
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  • The study investigated air contamination in Lhasa from biomass combustion and suspended dust, focusing on particulate matter (PM) emissions from seven non-fossil pollution sources.
  • Researchers found that biomass combustion contributed significantly to toxic metal concentration, particularly in PM with a notable peak in the 0.4-1 µm size range.
  • Enrichment factor analysis revealed that metals like Cr, Cu, Zn, and Pb from biomass combustion were highly enriched, especially in smaller particles, indicating a strong human impact on air quality.
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  • This study analyzes the changes in nutritional content and microbial communities in Tibetan sheep and goat milk during the first 56 days of lactation, highlighting fluctuations in milk fat, protein, lactose, and galactose over time.
  • The research utilized 16S rRNA gene sequencing, revealing a progressive increase in microbial diversity and distinct microbial clusters at various lactation stages, with common core microbes identified in both species.
  • The findings indicate significant correlations between certain microbial genera and specific milk nutrients, suggesting a complex relationship between milk composition and microbial dynamics that could inform livestock management practices.
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To investigate the vertical distribution of volatile organic compounds (VOCs) concentrations in the Lhasa valley region, an intensive measurement campaign was first conducted in summer using a tethered balloon. The results showed that the average concentration of surface VOCs was 49.1 ± 30.

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Due to the harsh environment in the Tibetan Plateau, traditional grazing greatly limits the growth potential of local animals and causes severe ecosystem degradation. This is an urgent issue to be solved, which requires alternative strategies for grazing animals in the Tibetan alpine pastoral livestock systems. This study aimed to investigate the effects of different feeding strategies on growth performance and ruminal microbiota-host interactions in the local breed of sheep (Gangba sheep).

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Tibetan sheep have lived on the Qinghai-Tibetan Plateau for thousands of years and have good adaptability to the hypoxic environment and strong disease resistance. However, the molecular mechanism by which Tibetan sheep adapt to this extreme environment, especially the role of genetic regulation, is still unknown. Emerging evidence suggests that long noncoding RNAs (lncRNAs) participate in the regulation of a diverse range of biological processes.

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sp. belongs to Coleoptera, Curculionidae, Leptomias Faust. It is mainly distributed in the Himalayas and Yarlung Zangbo River valleys in Tibet.

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Most sheep breeding programs designed for the tropics and sub-tropics have to take into account the impacts of environmental adaptive traits. However, the genetic mechanism regulating the multiple biological processes driving adaptive responses remains unclear. In this study, we applied a selective sweep analysis by combing 1% top values of F and ZHp on both altitude and geographic subpopulations (APS) in 636 indigenous Tibetan sheep breeds.

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To understand the physical and chemical characteristics, particle size distribution and sources of size-separated aerosols in Lhasa, which is located on the Tibetan Plateau (TP), six sizes of aerosol samples were collected in Lhasa in 2014. Ca, NH, NO, SO and Cl were the dominant ions. The ratio of cation equivalents (CE) to anion equivalents (AE) for each particle size segment indicated that the atmospheric aerosols in Lhasa were alkaline.

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An imidazolate-bridged homodinuclear complex, {[Cu(L)(H2O)]2(im)}(ClO4)3 (1), assembled with beta-cyclodextrin (betaCD) and its guanidinium-containing derivative (betaGCD), and thus a helical inclusion complex, {[Cu(L)(H2O)(betaCD)]2(im)}(ClO4)3 (2), were successfully isolated and structurally characterized. Structural analysis showed that each Cu(II) ion has a distorted square pyramidal N4Ow coordination sphere and forms a chiral chain through hydrogen-bonding and hydrophobic interactions. The UV-vis data showed that such a chain can provide the imidazolate bridge additional stability and results in the dissociation equilibrium taking place at the physiological pH.

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