Synopsis of recent research by authors named "Zhuofan Lei"
- Zhuofan Lei's recent research focuses on the interplay between inflammation and neurodegeneration, particularly in the contexts of spinal cord injuries (SCI) and sepsis-associated encephalopathy (SAE), emphasizing the role of extracellular vesicles and specific molecular mechanisms in neuroinflammation.
- Findings indicate that age and genetic factors significantly influence inflammatory responses and recovery outcomes after injuries, with aging exacerbating neuroinflammation and complicating neurological recovery in affected individuals.
- The studies suggest potential therapeutic targets, such as the integrin CD11b and natural compounds like dioscin, which show promise in mitigating oxidative stress and inflammation in various injury models, highlighting their protective effects on neuronal health.
