Publications by authors named "Zhuo-Wen Chen"

Gastrodia elata Bl. is a widely used traditional Chinese medicine known for its medicinal properties. However, during the drying process, G.

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Multiple primary lung cancer (MPLC) is an increasingly prevalent subtype of lung cancer. According to recent genomic studies, the different lesions of a single MPLC patient exhibit functional similarities that may reflect evolutionary convergence. We perform whole-exome sequencing for a unique cohort of MPLC patients with multiple samples from each lesion found.

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Objective: To explore the clinical effects of oral small dose of cyclophosphamide (CTX) in the treatment of T-cell large granular lymphocytic leukemia (T-LGLL) accompanied with pure red cell aplasia (PRCA).

Methods: The clinical features, characteristics of laboratory examinations and the process of oral small dose of CTX treatment after the ineffective treatment of cyclosporine A combining with prednisone in 1 case of T-LGLL with PRCA were reported and discussed with related references.

Results: The elderly female patient had indolent process, mainly presenting with anemia and significant low hyperplasia of bone marrow erythrocyte cells.

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Article Synopsis
  • Researchers wanted to see if a new treatment called R-CEOP70 was just as good as the standard R-CHOP50 for a type of cancer called diffuse large B-cell lymphoma, but with less harm to the heart.
  • They studied different age groups, randomly assigning younger patients (16-60) to three treatment types and older patients (61-80) to two types, all while keeping the study conditions fair.
  • The main goal was to check if these treatments helped patients live without cancer spreading for at least 2 years, and the findings were recorded for further analysis.
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Objective: To explore the effects of IFN-γ on pulmonary GVHD after hematopoietic stem cell transplantation (HSCT).

Methods: The mouse GVHD models were established by using C57BL/6J, B6D2F1 mice and different HSCT. According to HSCT modes, the mice were divided into 3 groups: syngeneic HSCT group(C57BL/6J→C57BL/6J), allogeneic HSCT group (C57BL/6J→B6D2F1) and IFN-γ allogeneic HSCT group (IFN-γ →C57BL/6J→B6D2F1).

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