The association between weekend warrior physical activity pattern and albuminuria in hypertensive patients.

Background: Albuminuria, a critical and sensitive indicator of vascular injury, has been linked to early kidney damage in patients with hypertension. High-quality physical activity (PA) may reduce urinary albumin excretion. Yet, the connection between PA patterns and albuminuria is still not well understood.

Physiological and molecular mechanisms of leaf response to high-temperature stress in high-temperature-resistant soybean varieties.

Background: With increasing global limate warm, high temperature (HT) is one of limiting factors for soybean yield and quality. Exploring HT resistance-related functional genes and their corresponding molecular mechanisms is of great value. In our previous report, compared with HD14 (HT sensitive), JD21 is an HT-resistant variety, and further analysis of the transcriptome and proteome has revealed the HT tolerance mechanism of JD21 anthers.

Co-application of cadmium-immobilizing bacteria and organic fertilizers alter the wheat root soil chemistry and microbial communities.

Cadmium contamination poses a significant risk to soil ecosystems in certain parts of the world. Using eco-friendly fertilizers alongside beneficial microorganisms offers a viable solution to mitigate Cd pollution in agricultural soil. This study used an outdoor experiment to evaluate the impact of administering a Cd-immobilizing bacterial (Bacillus) inoculant with two biologically-enriched organic fertilizers (either fermentative edible fungi residue or fermented cow dung) on wheat plants and associated microbial populations in a field contaminated with Cd.

Bacterial community drives soil organic carbon transformation in vanadium titanium magnetite tailings through remediation using Pongamia pinnata.

With continuous mine exploitation, regional ecosystems have been damaged, resulting in a decline in the carbon sink capacity of mining areas. There is a global shortage of effective soil ecological restoration techniques for mining areas, especially for vanadium (V) and titanium (Ti) magnetite tailings, and the impact of phytoremediation techniques on the soil carbon cycle remains unclear. Therefore, this study aimed to explore the effects of long-term Pongamia pinnata remediation on soil organic carbon transformation of V-Ti magnetite tailing to reveal the bacterial community driving mechanism.

Inhibition of Wilt in Cotton through the Application of ZL6 Derived from Fermentation Residue of Kitchen Waste.

To isolate and analyze bacteria with wilt-resistant properties from the fermentation residue of kitchen wastes, as well as explore their potential for new applications of the residue. A total of six bacterial strains exhibiting wilt-resistant capabilities were isolated from the biogas residue of kitchen waste fermentation. Using a polyphasic approach, strain ZL6, which displayed the highest antagonistic activity against cotton wilt, was identified as belonging to the .

Polystyrene microplastics promote intestinal colonization of Aeromonas veronii through inducing intestinal microbiota dysbiosis.

The premise that pathogen colonized microplastics (MPs) can promote the spread of pathogens has been widely recognized, however, their role in the colonization of pathogens in a host intestine has not been fully elucidated. Here, we investigated the effect of polystyrene MPs (PS-MPs) on the colonization levels of Aeromonas veronii, a typical aquatic pathogen, in the loach (Misgurnus anguillicaudatus) intestine. Multiple types of MPs were observed to promote the intestinal colonization of A.

Cilostazol protects against degenerative cervical myelopathy injury and cell pyroptosis via TXNIP-NLRP3 pathway.

Degenerative cervical myelopathy (DCM) is one of the most common and serious neurological diseases. Cilostazol has protective effects of anterior horn motor neurons and prevented the cell apoptosis. However, there was no literatures of Cilostazol on DCM.

Brain-derived neurotrophic factor gene polymorphism affects cognitive function and neurofilament light chain level in patients with subcortical ischaemic vascular dementia.

Objective: To investigate the effects of brain-derived neurotrophic factor (BDNF) gene polymorphism on cognitive function, neuroimaging and blood biological markers in patients with subcortical ischaemic vascular dementia (SIVD).

Methods: A total of 81 patients with SIVD were included. According to their BDNF gene polymorphism, the participants were divided into the Val/Val ( = 26), Val/Met ( = 35), and Met/Met ( = 20) groups.

Small RNA-Seq to Unveil the miRNA Expression Patterns and Identify the Target Genes in .

, renowned for its medicinal properties, relies on adventitious roots and hairy roots as crucial sources for the production of ginsenosides. Despite the widespread utilization of ginseng, investigations into its miRNAs have remained scarce. To address this gap, two samples of ginseng adventitious roots and ginseng hairy roots were collected, and subsequent construction and sequencing of small RNA libraries of ginseng adventitious roots and hairy roots were performed using the Illumina HiSeq X Ten platform.

Integrated transcriptome and proteome analysis reveals molecular responses of soybean anther under high-temperature stress.

It is well documented that high temperature (HT) severely affects the development of soybean male reproductive organs. However, the molecular mechanism of thermo-tolerance in soybean remains unclear. To explore the candidate genes and regulatory mechanism of soybean response to HT stress and flower development, here, the anthers of two previously identified HT-tolerant (JD21) and HT-sensitive (HD14) varieties were analyzed by RNA-seq.

Suppressing Viscous Fingering in Porous Media with Wetting Gradient.

The viscous fingering phenomenon often occurs when a low-viscosity fluid displaces a high-viscosity fluid in a homogeneous porous media, which is an undesirable displacement process in many engineering applications. The influence of wetting gradient on this process has been studied over a wide range of capillary numbers (7.5 × 10 to 1.

A neuropsychological profile and its correlation with neuroimaging markers in patients with subcortical ischaemic vascular dementia.

Objectives: Cognitive and neuroimaging assessments are still the main clinical practice methods for screening and diagnosing vascular dementia (VaD) patients. This study aimed to establish the neuropsychological characteristics of mild-to-moderate subcortical ischaemic vascular dementia (SIVD) patients, find an optimal cognitive marker for differentiating them from Alzheimer's disease (AD) patients, and explore the correlation between cognitive function and total small vessel disease (SVD) burden.

Methods: SIVD (n = 60) and AD (n = 30) patients and cognitively unimpaired healthy controls (HCs; n = 30) were recruited from our longitudinal MRI AD and SIVD study (ChiCTR1900027943) and received a comprehensive neuropsychological assessment and a multimodal MRI scan.

The relationships between fractal parameters of soil particle size and heavy-metal content on alluvial-proluvial fan.

The particle size distribution (PSD) of soil is an important factor in determining heavy-metal content, mobility, and transformation. One method of describing the soil PSD is applying fractal theory. This study explored the use of fractal theory to characterize soil PSD in the alluvial-proluvial fan located downstream of the Yangshuo lead‑zinc mine.

Turbulent CFD Simulation of Two Rotor-Stator Agitators for High Homogeneity and Liquid Level Stability in Stirred Tank.

Good solid-liquid mixing homogeneity and liquid level stability are necessary conditions for the preparation of high-quality composite materials. In this study, two rotor-stator agitators were utilized, including the cross-structure rotor-stator (CSRS) agitator and the half-cross structure rotor-stator (HCSRS) agitator. The performances of the two types of rotor-stator agitators and the conventional A200 (an axial-flow agitator) and Rushton (a radial-flow agitator) in the solid-liquid mixing operations were compared through CFD modeling, including the homogeneity, power consumption and liquid level stability.

Visual LAMP method for the detection of Vibrio vulnificus in aquatic products and environmental water.

Background: A visual, rapid, simple method was developed based on a loop-mediated isothermal amplification (LAMP) assay to detect Vibrio vulnificus in aquatic products and aquaculture waters.

Results: Genomic DNA was extracted from Vibrio vulnificus using the boiling method, and optimized primers were used to detect the gyrB gene using a visual LAMP method. The sensitivity of the assay was 10 fg/μL, and the obtained results were stable and reliable.

Pelargonidin inhibits vascularization and metastasis of brain gliomas by blocking the PI3K/AKT/mTOR pathway.

Pelargonidin has attracted much attention in many cancers. Whether the growth of glioma inhibited by pelargonidin is related to the PI3K/AKT/mTOR pathway is unknown. To examine this, we performed both and studies.

Validation of qPCR from a crude extract for the rapid detection of .

Unlabelled: White spot disease (WSD) has posed a serious threat to the China and the global shrimp aquaculture. In order to diagnose (WSSV) early and prevent the spread and outbreak of WSD, it is necessary to establish a highly sensitive WSSV diagnosis method suitable for shrimp farming sites. In this study, a pre-amplification qPCR assay from the crude extract of samples heated lysis was established, which was further compared with the universal qPCR assay to verify the shrimp samples.

Efficiency of oro-facial myofunctional therapy in treating obstructive sleep apnoea: A meta-analysis of observational studies.

Objective: The literature on oro-facial myofunctional therapy (OMT) in children and adults with obstructive sleep apnoea (OSA) was systematically reviewed to investigate the effects of OMT on patients with OSA by age and disease severity to verify the effect of OMT on OSA.

Data Sources: All the comparative literature was retrieved from the PubMed, Embase and Cochrane libraries.

Method: We searched the articles published up to 12 February 2022 and followed the preferred reporting project for systematic review and meta-analysis of reports.

Prognostic Value of c-MYC Expression in Patients with Peripheral Neuroblastic Tumors.

Objective: Neuroblastic tumors are the most common solid tumors in children. The aim of this study was to explore the prognostic value of immunostaining for cellular-myelocytomatosis viral oncogene (c-MYC) expression in patients with peripheral neuroblastic tumors (NTs).

Methods: A retrospective study was conducted to compare the expression of c-MYC detected by immunohistochemistry and v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog () by fluorescence in situ hybridization among 177 cases of NTs and determine the associations of c-MYC and with the clinical stages, morphological types, and survival rates of NTs.

Characterization of the complete chloroplast genome of (Araliaceae) as an herb in China.

is a highly valued woody herb medicinal plant belonging to the family Araliaceae, which is also the popular edible plant in China. In this paper, the chloroplast genome of was completed. The complete chloroplast genome of was 156,768 bp in length as a circle.

Characterization and genetic analysis of the complete chloroplast genome of (Magnoliaceae: Schisandra), an herbal medicine from China.

is a deciduous woody vine plant that has been used in traditional medicine for thousands of years in China. In this study, we researched the complete chloroplast genome of The complete chloroplast genome length is 147,779 bp, containing a large single-copy region (LSC) of 97,352bp, a small single-copy region (SSC) of 20,313 bp, and a pair of inverted repeat (IR) regions of 15,057 bp. The overall nucleotide composition is: A of 29.

Plasma copeptin and functional outcome in patients with ischemic stroke and type 2 diabetes.

Background: The activation of the arginine vasopressin system may be involved in the pathology of stroke and diabetes. In this study, we therefore evaluated the short-term prognostic value of early measurement of plasma copeptin levels in Chinese patients with type 2 diabetes mellitus (T2DM) and acute ischemic stroke (AIS).

Methods: From July 2014 to June 2015, all T2DM patients with first-ever AIS were included.

Celastrol, a triterpene extracted from Tripterygium wilfordii Hook F, inhibits platelet activation.

Celastrol is an active ingredient of the traditional Chinese medicinal plant, Tripterygium wilfordii Hook F, which is known especially for its anti-inflammatory effects. However, on the cellular and molecular levels, celastrol's mechanism of action is only poorly understood. Because platelets contribute to inflammatory events, this study investigates the effects of celastrol on platelet function using flow cytometry, aggregometry, and adhesion assays.

Application of microcapsulation technology to the preparation of carbon foam.

Microcapsules were prepared by polymerization and microcapsulation. Tetraethyl orthosilicate was used as the core material and phenolic resin was used as the wall material in an emulsion system of polyacrylic and tetraethyl orthosilicate. The obtained microcapsules were slowly heated such that the core material was released by evaporation, leaving hollow-core spheres.