Publications by authors named "Zhuo Lan"

Article Synopsis
  • The study investigates a zoonotic parasite prevalent in East Asia by analyzing genetic variation using mitochondrial and ribosomal DNA sequences.
  • It identified distinct haplotypes across different regions, revealing that these haplotypes do not cluster by country, indicating genetic diversity.
  • The findings suggest the parasite's population is increasing with low genetic variation, providing insights for future disease control and epidemiology.
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This study explored the effects of long-term cold stress on aortic vascular function in guinea pigs. Research Methods: Hartley guinea pigs (n=32) were divided into following groups: atherosclerosis (AS), cold stress (CS), and menthol-stimulated (M) and control (C). On days 1, 15, 30, 45, and 60, guinea pigs in the AS, CS, and M groups were intraperitoneally injected with bovine serum albumin.

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  • The study focuses on the mitochondrial genome of a trematode parasite from wood frogs, marking the first complete sequencing for the family Pleurogenidae, which is significant due to high infection rates in these frogs and their ecological importance.* -
  • The mitochondrial genome is circular and comprises 15,043 base pairs with 36 genes, including 12 protein-coding genes, and shows a strong bias towards adenine and thymine (63.75% A+T content).* -
  • Phylogenetic analysis indicates that this trematode is more closely related to Prosthogonimidae than to Eucotylidae, providing valuable genetic data for future research on Xiphidiata trematodes.*
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  • - The study investigates the global prevalence and risk factors of fascioliasis (liver disease caused by the Fasciola parasite) in humans and domestic ruminants, finding that 17% of cattle, 13% of sheep, and 5% of humans are affected.
  • - Researchers analyzed 4422 articles, narrowing it down to 371 relevant studies, and employed various statistical methods to assess prevalence and identify risk factors, particularly focusing on altitude and age.
  • - The findings highlight the widespread nature of fascioliasis and emphasize the urgent need for targeted prevention strategies based on identified risk factors.
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  • The study investigates the prevalence of important diarrheal protozoan pathogens in cattle fecal samples collected from Heilongjiang Province, highlighting their global health risks to humans and animals.
  • The research sampled 1,155 cattle, revealing infection rates of 5.5% for one protozoan species, 3.8% for another, and 6.5% for a third, with several genetic variants identified among them.
  • Findings indicate that some protozoan species are zoonotic, meaning they can be transmitted from animals to humans, which raises public health concerns in the affected areas.
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Prosthogonimiasis poses a threat to the reproductive system of poultry and wild birds, which are the definitive hosts of the parasite causing this disease. However, the parasite infection of the second intermediate host (dragonfly), the primary vector of this pathogen, is rarely reported. In this study, the prevalence of Prosthogonimus infection in dragonflies was investigated from June 2019 to October 2022 in Heilongjiang Province, northeast China.

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Globally, the species of are key components of ectomycorrhizal ecosystems. Some of them are widely known as poisonous or edible fungi. Although many new species from China have been described, the species diversity of Yanshan Mountains remains unknown.

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Screening bioactive compounds from natural products is one of the most effective ways for new drug research and development. However, obtaining a single extract component on a large scale and with high purity from a complex matrix is still an arduous and challenging task. Herein, one metal mediated magnetic molecularly imprinted polymer (mMIP) was rationally designed and prepared for specifically capturing Aristolochic acid I (AAI).

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Fasciolosis is a significant zoonotic and common parasitic disease for animals and humans, creating public health concerns worldwide. This study retrieved articles related to the occurrence of and in sheep and goats in China by searching five databases: PubMed, ScienceDirect, the Chinese National Knowledge Infrastructure (CNKI), Wanfang Data, and the VIP Chinese Journal Database. A total of 60 valid articles were captured.

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It is of great significance to develop a drug carrier that effectively targets chemotherapeutic drugs to the tumor site, improves therapeutic efficacy and reduces side effects associated with high-dose medicines. In the present study, an intelligent drug carrier system, FA-β-CD/DOX@Cu@GA@FeO, was synthesized by skillfully introducing metal ions as a bridge base. The performance of the prepared FA-β-CD@Cu@GA@FeO metal-polymer-coordinated nanocomplexes were determined by UV-visible spectroscopy, NMR, FT-IR, XPS, VSM, DLS, and TEM analysis.

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(, ) is a monotypic genus with a previously unknown systematic position. In this report, two new species are proposed, and These new taxa are proposed based on morphological characteristics evident via light microscopy and molecular data. Multi-locus phylogenetic analyses (ITS rDNA, nrLSU rDNA, , and ) show that specimens recently collected in Yunnan Province, China are closely related to .

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Species of the genus are key components of ectomycorrhizal ecosystems worldwide, some of which are famous edible fungi. Although many new species have been described in China, their diversity in North China is still poorly known. Based on the morphology observation of specimens and molecular phylogenetic analyses, combined with the current classification frame of , six new species of subgenus are proposed from the Yanshan Mountains in northern Beijing and northern Hebei Province of China in this study: viz.

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Fascioliasis is a foodborne zoonotic disease generally caused by the parasitic flukes Fasciola gigantica and Fasciola hepatica in class Trematoda. An "intermediate" Fasciola forms between F. gigantica and F.

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Article Synopsis
  • A significant parasitic nematode of cranes, classified as part of the Spirurina suborder, has a controversial classification that has persisted for over a century.
  • The complete mitochondrial genome of this nematode was sequenced, revealing a circular structure with 13,709 bp, containing 12 protein-coding genes and high AT content similar to other Spirurina species.
  • Phylogenetic analyses showed that this nematode is more closely related to Spiruroidea than to Thelazioidea, providing valuable genetic markers for future research on Spirurina nematodes.
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is a widespread pathogen that is known for its harmful effects on the health and productivity of ruminant animals. To identify the proteins present in all periods of infection with but not in those with by shotgun liquid chromatography-tandem mass spectrometry (LC-MS/MS), we collected the ESPs and sera of and . In this study, the sheep were artificially infected with and the sera were collected at five different periods: 3 days post-infection (dpi), 7 dpi, 21 dpi, 63 dpi, and 112 dpi.

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Coronocyclus labiatus and Cylicodontophorus bicoronatus are two significant horse parasitic nematodes which are classified into subfamily Cyathostominae, family Strongylidae, however, the classification of these nematodes has been controversial for more than a century. Mitochondrial (mt) genomes are considered valuable sources for parasite taxonomy, population genetics, and systematics studies. In the present study, the mt genomes of Co.

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Pharmacovigilance aims to identify adverse drug reactions using postmarket surveillance data under real-world conditions of use. Unlike passive pharmacovigilance, which is based on largely voluntary (and hence incomplete) spontaneous reports of adverse drug reactions with limited information on patient characteristics, active pharmacovigilance is based on electronic health records containing detailed information about patient populations, thereby allowing consideration of modifying factors such as polypharmacy and comorbidity, as well as sociodemographic characteristics. With the present shift toward active pharmacovigilance, statistical methods capable of addressing the complexities of such data are needed.

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