BTF3L4 Overexpression Mediates APAP-induced Liver Injury in Mouse and Cellular Models.

Background And Aims: Acetaminophen (APAP)-induced liver injury (AILI) has an increasing incidence worldwide. However, the mechanisms contributing to such liver injury are largely unknown and no targeted therapy is currently available. The study aimed to investigate the effect of BTF3L4 overexpression on apoptosis and inflammation regulation and .